Herpes simplex encephalitis
MONDO:0012521Herpes simplex virus encephalitis (HSE) is caused by the infection of the central nervous system by Herpes simplex virus (HSV) that could have a devastating clinical course and a potentially fatal outcome particularly with delay or lack of treatment. HSV often involves the frontal and temporal lobes, usually asymmetrically, resulting in personality changes, cognitive impairment, aphasia, seizures, and focal weakness.
Also known as: Encephalitis, Herpes Simplex, HSE, HSV encephalitis, HSVE, Herpes simplex meningo-encephalitis, Herpes simplex neuroinvasion, Simplexvirus caused infectious encephalitis, Simplexvirus infectious encephalitis
10 clinical trials for this condition and its sub-types.
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Scientists compare immune responses to viral and bacterial infections in ICU patients
Knowledge-focused OngoingThis study looks at how the immune system of patients in the intensive care unit (ICU) responds to severe infections caused by viruses or bacteria. Researchers will take extra blood samples from 38 adults to analyze immature granulocytes, a type of immune cell. The goal is to see…
Phase: NA • Sponsor: University Hospital, Limoges • Aim: Knowledge-focused
Last updated Jun 28, 2026 00:00 UTC
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Massive review of viral meningitis cases aims to sharpen diagnosis
Knowledge-focused OngoingThis study looks back at 4000 patients who had a suspected viral infection of the brain or spinal cord. Researchers will analyze which viruses were found and how the illness progressed in different groups, including children, adults, and people with weakened immune systems. The g…
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC