Herpes simplex encephalitis
MONDO:0012521Herpes simplex virus encephalitis (HSE) is caused by the infection of the central nervous system by Herpes simplex virus (HSV) that could have a devastating clinical course and a potentially fatal outcome particularly with delay or lack of treatment. HSV often involves the frontal and temporal lobes, usually asymmetrically, resulting in personality changes, cognitive impairment, aphasia, seizures, and focal weakness.
Also known as: Encephalitis, Herpes Simplex, HSE, HSV encephalitis, HSVE, Herpes simplex meningo-encephalitis, Herpes simplex neuroinvasion, Simplexvirus caused infectious encephalitis, Simplexvirus infectious encephalitis
10 clinical trials for this condition and its sub-types.
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Researchers review best acyclovir dose for obese patients with rare brain infection
Knowledge-focused CompletedThis completed study reviewed medical records of 50 obese adults with HSV encephalitis (a brain infection) to see how different ways of calculating acyclovir dose affect survival. Researchers looked at patients treated between 2013 and 2019 at six hospitals. The goal was to find …
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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MRI contrast dye may skew brain scans, study finds
Knowledge-focused CompletedThis study looked at how gadolinium, a dye used in MRI scans, changes the QSM signal in the brain's white matter. 73 patients with inflammatory central nervous system conditions had MRI scans before and after receiving gadolinium. The goal was to measure any differences in the si…
Sponsor: Fondation Ophtalmologique Adolphe de Rothschild • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC