Herpes labialis
MONDO:0043653A lesion caused by type 1 or type 2 herpes simplex virus, typically involving the oralfacial region.
Also known as: cold sore, cold sores, herpes labialis, Herpes simplex, labial, Sore, cold, Sores, cold, blister, fever, blisters, fever
33 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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New cold sore cream shows promise in small study
Disease control CompletedThis study tested a cream containing acyclovir and penciclovir against an over-the-counter cream (Abreva) for preventing cold sores caused by UV light. Forty adults with a history of cold sores were exposed to UV light to trigger an outbreak, then treated with one of the creams. …
Phase: PHASE2 • Sponsor: University of Utah • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Rural patients get Hospital-Level care at home in landmark trial
Disease control CompletedThis study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…
Phase: NA • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Can eye drops beat abreva for cold sores? small study says maybe
Disease control CompletedThis study tested whether EDTA eye drops can shorten cold sore outbreaks compared to the over-the-counter cream Abreva. Ten adults with a history of sun-triggered cold sores were randomly assigned to one of the two treatments. Researchers tracked how many days it took for each co…
Phase: PHASE2 • Sponsor: University of Utah • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New rapid test for infection and inflammation put to the test
Diagnosis CompletedThis study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…
Sponsor: LumiraDx UK Limited • Aim: Diagnosis
Last updated Jun 27, 2026 13:07 UTC
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New PET scan technique aims to sniff out hidden infections
Diagnosis CompletedThis early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…
Sponsor: Johns Hopkins University • Aim: Diagnosis
Last updated Jun 27, 2026 08:03 UTC
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New gum tablet could speed up cold sore healing
Symptom relief CompletedThis study tested a single acyclovir tablet that sticks to the gum to treat cold sores (herpes labialis) in 2020 adults with frequent outbreaks. Participants applied the tablet or a placebo at home and tracked healing over 14 days. The goal was to see if the drug shortens the tim…
Phase: PHASE3 • Sponsor: Bayer • Aim: Symptom relief
Last updated Jun 26, 2026 13:09 UTC
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ICU antibiotic dosing: what really matters?
Knowledge-focused CompletedThis study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC