Herpes labialis
MONDO:0043653A lesion caused by type 1 or type 2 herpes simplex virus, typically involving the oralfacial region.
Also known as: cold sore, cold sores, herpes labialis, Herpes simplex, labial, Sore, cold, Sores, cold, blister, fever, blisters, fever
7 clinical trials for this condition and its sub-types.
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Broader categories
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New cold sore cream shows promise in small study
Disease control CompletedThis study tested a cream containing acyclovir and penciclovir against an over-the-counter cream (Abreva) for preventing cold sores caused by UV light. Forty adults with a history of cold sores were exposed to UV light to trigger an outbreak, then treated with one of the creams. …
Phase: PHASE2 • Sponsor: University of Utah • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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Can eye drops beat abreva for cold sores? small study says maybe
Disease control CompletedThis study tested whether EDTA eye drops can shorten cold sore outbreaks compared to the over-the-counter cream Abreva. Ten adults with a history of sun-triggered cold sores were randomly assigned to one of the two treatments. Researchers tracked how many days it took for each co…
Phase: PHASE2 • Sponsor: University of Utah • Aim: Disease control
Last updated Jun 27, 2026 07:56 UTC
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New gum tablet could speed up cold sore healing
Symptom relief CompletedThis study tested a single acyclovir tablet that sticks to the gum to treat cold sores (herpes labialis) in 2020 adults with frequent outbreaks. Participants applied the tablet or a placebo at home and tracked healing over 14 days. The goal was to see if the drug shortens the tim…
Phase: PHASE3 • Sponsor: Bayer • Aim: Symptom relief
Last updated Jun 26, 2026 13:09 UTC