Gram-positive bacterial infections
MONDO:0021679Infections caused by bacteria that retain the crystal violet stain (positive) when treated by the gram-staining method.
Also known as: Gram Positive bacterial infections, Gram-positive bacterial infection, Gramme Positive bacterial infections, bacterial infection, Gram-positive, bacterial infections, Gram Positive, bacterial infections, Gram-positive, bacterial infections, Gramme Positive, infection, Gram-positive bacterial
263 clinical trials for this condition and its sub-types.
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Broader categories
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New hope for recurring c. diff: which treatment works best?
Disease control TerminatedThis study tested three different antibiotic regimens for people with recurrent Clostridium difficile infection (C. diff), a serious gut infection that keeps coming back. The goal was to see if newer drugs like fidaxomicin or a tapered/pulsed course of vancomycin work better than…
Phase: PHASE4 • Sponsor: VA Office of Research and Development • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Promising c. diff drug trial halted after just 3 patients
Disease control TerminatedThis study tested a new drug called REC-3964 to see if it could prevent repeat Clostridioides difficile (C. diff) infections in adults. Only 3 people were enrolled before the trial was stopped early. The goal was to check safety and whether the drug helped people stay infection-f…
Phase: PHASE2 • Sponsor: Recursion Pharmaceuticals Inc. • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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New inhaled drug aimed at stubborn lung infection shows promise, but trial halted early
Disease control TerminatedThis phase 3 study tested an inhaled form of the antibiotic clofazimine added to standard therapy for people with MAC lung disease that did not respond to previous treatment. The goal was to see if the drug could clear the infection from sputum cultures and improve quality of lif…
Phase: PHASE3 • Sponsor: Mannkind Corporation • Aim: Disease control
Last updated Jun 27, 2026 07:57 UTC
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Vaccine antibody check: how long does protection last?
Knowledge-focused TerminatedThis study followed women who previously received 1 to 3 doses of an experimental Group B Strep (GBS) vaccine. The goal was to see how long their immune antibodies lasted by taking yearly blood samples for 2 to 5 years. No new vaccine or treatment was given—only observation.
Sponsor: Minervax ApS • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Sticker shock: simple reminder may cut unnecessary IV antibiotic use
Knowledge-focused TerminatedThis study tested whether placing a reminder sticker on the charts of adult hospital patients receiving IV fluoroquinolone antibiotics would encourage doctors to switch them to oral pills sooner. The trial involved 168 patients at a single hospital in Thailand. Unfortunately, the…
Phase: NA • Sponsor: Mahidol University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC