Fuchs' endothelial dystrophy
MONDO:0005321Fuchs endothelial corneal dystrophy (FECD) is the most frequent form of posterior corneal dystrophy and is characterized by excrescences on a thickened Descemet membrane (corneal guttae), generalized corneal edema, with gradually decreased visual acuity.
Also known as: Endoepithelial corneal dystrophy, FECD, Fuchs endothelial dystrophy, corneal dystrophy, Fuchs endothelial, late hereditary endothelial dystrophy, Fuchs endothelial corneal dystrophy
43 clinical trials for this condition and its sub-types.
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Eye transplant showdown: which surgery saves sight best?
Disease control OngoingThis study compares two types of corneal transplant surgery (UT-DSAEK and DMEK) in 160 people with Fuchs dystrophy, a condition that clouds the cornea. It also tests whether a drug called rho-kinase inhibitor can reduce loss of important eye cells after surgery. The goal is to fi…
Phase: PHASE3 • Sponsor: Stanford University • Aim: Disease control
Last updated Jun 27, 2026 12:30 UTC
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Contact lens stress test for fuchs dystrophy eyes
Knowledge-focused TerminatedThis study aimed to compare how corneas with Fuchs endothelial corneal dystrophy (FECD) and healthy corneas swell and recover after wearing a contact lens for three hours. Researchers planned to measure corneal thickness before and after the lens was removed, tracking swelling an…
Phase: PHASE1, PHASE2 • Sponsor: Massachusetts Eye and Ear Infirmary • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:09 UTC
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Does donor diabetes impact corneal transplant outcomes?
Knowledge-focused ENROLLING_BY_INVITATIONThis study looks at whether corneas from donors with diabetes work as well as those from donors without diabetes after a specific type of corneal transplant called DMEK. Researchers will track 570 participants for 5 years to measure cell loss and overall transplant success. The g…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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Free eye tests aim to catch vision loss early in harlem and washington heights
Knowledge-focused OngoingThis study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC