Familial dilated cardiomyopathy
MONDO:0016333A a genetic form of heart disease that occurs when heart (cardiac) muscle becomes thin and weakened in at least one chamber of the heart, causing the open area of the chamber to become enlarged (dilated). As a result, the heart is unable to pump blood as efficiently as usual. To compensate, the heart attempts to increase the amount of blood being pumped through the heart, leading to further thinning and weakening of the cardiac muscle. Over time, this condition results in heart failure.
Also known as: hereditary dilated cardiomyopathy, DCM, dilated cardiomyopathy, familial, hypokinetic dilated cardiomyopathy, familial, idiopathic dilated cardiomyopathy
68 clinical trials for this condition and its sub-types, 7 tagged with Familial dilated cardiomyopathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Familial dilated cardiomyopathy
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Leber hereditary optic neuropathy 18 trials
1 sub-type
- Leber optic atrophy and dystonia 0 trials
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Familial isolated dilated cardiomyopathy 0 trials · 11 incl. sub-types
45 sub-types
- Dilated cardiomyopathy 1HH 5 trials
- Dilated cardiomyopathy 1A 2 trials
- Dilated cardiomyopathy 1C 1 trial
- Dilated cardiomyopathy 1FF 1 trial
- Dilated cardiomyopathy 1P 1 trial
- Dilated cardiomyopathy 3B 1 trial
- Cardiomyopathy, dilated, 2D 0 trials
- Cardiomyopathy, dilated, 2E 0 trials
- Cardiomyopathy, dilated, 2F 0 trials
- Cardiomyopathy, dilated, 2G 0 trials
- Cardiomyopathy, dilated, 2H 0 trials
- Cardiomyopathy, dilated, 2c 0 trials
- Dilated cardiomyopathy 1AA 0 trials
- Dilated cardiomyopathy 1B 0 trials
- Dilated cardiomyopathy 1BB 0 trials
- Dilated cardiomyopathy 1CC 0 trials
- Dilated cardiomyopathy 1D 0 trials
- Dilated cardiomyopathy 1DD 0 trials
- Dilated cardiomyopathy 1E 0 trials
- Dilated cardiomyopathy 1EE 0 trials
- Dilated cardiomyopathy 1G 0 trials
- Dilated cardiomyopathy 1GG 0 trials
- Dilated cardiomyopathy 1H 0 trials
- Dilated cardiomyopathy 1I 0 trials
- Dilated cardiomyopathy 1II 0 trials
- Dilated cardiomyopathy 1JJ 0 trials
- Dilated cardiomyopathy 1K 0 trials
- Dilated cardiomyopathy 1KK 0 trials
- Dilated cardiomyopathy 1L 0 trials
- Dilated cardiomyopathy 1M 0 trials
- Dilated cardiomyopathy 1NN 0 trials
- Dilated cardiomyopathy 1O 0 trials
- Dilated cardiomyopathy 1Q 0 trials
- Dilated cardiomyopathy 1R 0 trials
- Dilated cardiomyopathy 1S 0 trials
- Dilated cardiomyopathy 1U 0 trials
- Dilated cardiomyopathy 1V 0 trials
- Dilated cardiomyopathy 1W 0 trials
- Dilated cardiomyopathy 1X 0 trials
- Dilated cardiomyopathy 1Y 0 trials
- Dilated cardiomyopathy 1Z 0 trials
- Dilated cardiomyopathy 2A 0 trials
- Dilated cardiomyopathy 2B 0 trials
- Left ventricular noncompaction 10 0 trials
- Left ventricular noncompaction 8 0 trials
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Barth syndrome 5 trials
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Kearns-Sayre syndrome 5 trials
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Histiocytoid cardiomyopathy 3 trials
1 sub-type
- Cardiac lipidosis, familial 0 trials
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Emery-Dreifuss muscular dystrophy 1 trial · 3 incl. sub-types
4 sub-types
- Autosomal dominant Emery-Dreifuss muscular dystrophy 0 trials · 3 incl. sub-types Sub-types →
- Emery-Dreifuss muscular dystrophy 3, autosomal recessive 0 trials
- X-linked Emery-Dreifuss muscular dystrophy 0 trials Sub-types →
- Scapuloperoneal myopathy 0 trials Sub-types →
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Cardiomyopathy, dilated, 100 0 trials
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Cardiomyopathy, dilated, 1LL 0 trials
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Cardiomyopathy, dilated, 1MM 0 trials
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Cardiomyopathy, dilated, 1QQ 0 trials
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Cardiomyopathy, dilated, 2I 0 trials
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Cardiomyopathy, dilated, 2K 0 trials
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Cardiomyopathy, dilated, 2M 0 trials
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Cardiomyopathy, dilated, 2j 0 trials
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Cardiomyopathy, dilated, 2l 0 trials
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Cardiomyopathy, dilated, 3C 0 trials
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Dilated cardiomyopathy 1J 0 trials
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Hypertrophic cardiomyopathy 25 0 trials
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Myofibrillar myopathy 1 0 trials
Most studied deeper sub-types
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Can a new drug strengthen hearts weakened by genetic disease?
Disease control Recruiting nowThis study tests the long-term safety and effectiveness of an investigational drug called danicamtiv in adults with symptomatic genetic or familial dilated cardiomyopathy (DCM), a condition where the heart muscle weakens and enlarges. Participants who completed a prior 24-week st…
Phase 3 • Sponsor: Kardigan, Inc. • Aim: Disease control
Last updated Sep 04, 2026 00:00 UTC
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New heart device could boost pumping power without surgery
Disease control Recruiting nowThis study tests a small device called C-MIC that is implanted without open-heart surgery to help people with heart failure. It includes 22 adults with weak heart pumping (ejection fraction between 25% and 50%) despite standard medications. The device delivers microcurrents to th…
Sponsor: Berlin Heals GmbH • Aim: Disease control
Last updated Aug 13, 2026 00:00 UTC
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New pill aims to strengthen hearts in genetic cardiomyopathy
Disease control Recruiting nowThis study tests an experimental daily pill, danicamtiv, in 332 people with genetic or familial dilated cardiomyopathy (a weakened, enlarged heart). Participants take the drug or a placebo for about 6 months to see if it improves heart function and exercise ability. The goal is t…
Phase 2/3 • Sponsor: Kardigan, Inc. • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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5,000 heart patients to wear smart patches for Years-Long observation
Knowledge-focused Recruiting nowThis study will enroll 5,000 adults with chronic heart conditions like heart failure, high blood pressure, or aortic stenosis. Participants will wear a Prolaio digital health patch that monitors heart rate, breathing, and other vital signs. The goal is to observe how these condit…
Sponsor: Prolaio • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC
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Heart disease detective: 1,000-Person study hunts for hidden genetic triggers of sudden cardiac death
Knowledge-focused Recruiting nowThis study is looking for new genes and blood markers linked to arrhythmogenic cardiomyopathy (AVC), a genetic heart condition that can lead to heart failure and sudden cardiac arrest. Researchers will enroll 1,000 people, including patients with AVC or unexplained cardiac arrest…
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:25 UTC
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Virtual clinic aims to boost genetic testing in families with heart disease
Knowledge-focused Recruiting nowThis study tests an online clinic (eCG Family Clinic) that helps families with inherited heart conditions get genetic counseling and DNA testing from home. Researchers will see if more family members use the service and how satisfied they are compared to standard care. About 170 …
Sponsor: UMC Utrecht • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:38 UTC