New pill aims to strengthen hearts in genetic cardiomyopathy

NCT ID NCT07210723

Recruiting now Disease control Sponsor: Kardigan, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 07, 2026 · Updated 2 times

Summary

This study tests an experimental daily pill, danicamtiv, in 332 people with genetic or familial dilated cardiomyopathy (a weakened, enlarged heart). Participants take the drug or a placebo for about 6 months to see if it improves heart function and exercise ability. The goal is to control the disease, not cure it, as ongoing medication is expected.

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Conditions

The condition(s) this trial relates to.

familial dilated cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

SYMPTOMATIC GENETIC DILATED CARDIOMYOPATHY

Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

AP-HP Hopital Europeen Georges Pompidou
RECRUITING

Paris, 75015, France

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AP-HP Hopital Pitie-Salpetriere
RECRUITING

Paris, 75013, France

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Aarhus University Hospital
RECRUITING

Aarhus, 8200, Denmark

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Amsterdam UMC - Locatie AMC
RECRUITING

Amsterdam, 1105-AZ, Netherlands

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Azienda Ospedaliero-Universitaria Careggi
RECRUITING

Florence, 50134, Italy

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Azienda Sanitaria Universitaria Giuliano Isontina (ASU GI) - Ospedale di Cattinara
RECRUITING

Trieste, 34100, Italy

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Baylor College of Medicine
RECRUITING

Houston, Texas, 77030, United States

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Brigham and Women's Hospital
RECRUITING

Boston, Massachusetts, 02115, United States

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Cardiovascular Clinical Research Facility (CCRF)
RECRUITING

Oxford, OX3 9DU, United Kingdom

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Cedars Sinai
RECRUITING

Los Angeles, California, 90048, United States

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Columbia University Medical Center/ New York Presbyterian Hospital
NOT_YET_RECRUITING

New York, New York, 10027, United States

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Duke University Medical Center
RECRUITING

Durham, North Carolina, 27708, United States

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Erasmus MC
RECRUITING

Rotterdam, 3015 GD, Netherlands

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Glenfield Hospital
RECRUITING

Leicester, LE3 9QP, United Kingdom

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Hammersmith Hospital, Imperial College of London
RECRUITING

London, W12 0HS, United Kingdom

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Henry Ford Health System
RECRUITING

Detroit, Michigan, 48202, United States

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Hospital Clinico Universitario Virgen de la Arrixaca
RECRUITING

Murcia, 30120 El Palmar,, Spain

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Hospital Universitari de Bellvitge
RECRUITING

Barcelona, 08907, Spain

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Hospital Universitario Puerta de Hierro
RECRUITING

Majadahonda, Madrid, 20222, Spain

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Hospital Universitario Son Llatzer
RECRUITING

Palma de Mallorca, 7198, Spain

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Hospital Universitario Vall d'Hebron
RECRUITING

Horta-Guinardó, Barcelona, 08035, Spain

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Hospital Universitario Virgen de la Victoria
RECRUITING

Málaga, 29001, Spain

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Hospital Universitario Virgen del Rocio
RECRUITING

Seville, 41013, Spain

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Hospital Universitario de A Coruña
RECRUITING

A Coruña, 15006, Spain

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Istituto Clinico Humanitas
RECRUITING

Rozzano, 20089, Italy

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Krakowski Szpital Specjalistyczny im. sw. Jana Pawla II
RECRUITING

Krakow, 31-202, Poland

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Louisiana State University (LSU) Health Sciences Center
RECRUITING

New Orleans, Louisiana, 70112, United States

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Mayo Clinic - Jacksonville
RECRUITING

Jacksonville, Florida, 32224, United States

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Mayo Clinic Rochester
RECRUITING

Rochester, Minnesota, 55905, United States

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MedStar Washington Hospital Center
RECRUITING

Washington D.C., District of Columbia, 20010, United States

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NHS Greater Glasgow and Clyde
RECRUITING

Glasgow, G12 0YN, United Kingdom

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NYU Langone Health
RECRUITING

New York, New York, 10016, United States

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Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

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Odense University Hospital - Odense
RECRUITING

Odense, 5000, Denmark

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Oregon Health & Science University (OHSU)
RECRUITING

Portland, Oregon, 97239, United States

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Rigshospitalet
RECRUITING

Copenhagen, 1050, Denmark

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Royal Brompton Hospital
RECRUITING

London, SW3 6NP, United Kingdom

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Samodzielny Publiczny Zaklad Opieki Zdrowotnej Centralny Szpital Kliniczny Uniwersytetu Medycznego w Lodzi
RECRUITING

Lodz, 92-213, Poland

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Semmelweis Egyetem - Varosmajori Sziv es Ergyogyaszati Klinika
RECRUITING

Budapest, 1122, Hungary

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Sodersjukhuset AB
RECRUITING

Stockholm, 11883, Sweden

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St George's Hospital
RECRUITING

London, SW17 0QT, United Kingdom

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St. Bartholomew's Hospital
RECRUITING

London, EC1A, United Kingdom

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Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont
RECRUITING

Szeged, 6724, Hungary

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The Lindner Center for Research and Education at The Christ Hospital
RECRUITING

Cincinnati, Ohio, 45219, United States

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The Ohio State University Wexner Medical Center
RECRUITING

Columbus, Ohio, 43210, United States

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UCSF
RECRUITING

San Francisco, California, 94158, United States

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Universitair Ziekenhuis Antwerpen (UZA)
RECRUITING

Edegem, 2650, Belgium

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Universite Libre de Bruxelles (ULB) - Hopital Erasme
RECRUITING

Brussels, 1070, Belgium

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University Hospitals Bristol NHS Foundation Trust
RECRUITING

Bristol, BS1 3NU, United Kingdom

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University of Alabama Birmingham
RECRUITING

Birmingham, Alabama, 35233, United States

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University of California, San Diego (UCSD) - Medical Center
RECRUITING

San Diego, California, 92037, United States

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University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States

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University of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68106, United States

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University of Pennsylvania
RECRUITING

Philadelphia, Pennsylvania, 19104, United States

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Vanderbilt University Medical Center
RECRUITING

Nashville, Tennessee, 37232, United States

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Washington University in St. Louis
RECRUITING

St Louis, Missouri, 63110, United States

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