Familial cardiomyopathy
MONDO:0005217An instance of cardiomyopathy that is caused by an inherited modification of the individual's genome.
Also known as: hereditary cardiomyopathy
226 clinical trials for this condition and its sub-types, 2 tagged with Familial cardiomyopathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Familial cardiomyopathy
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Familial hypertrophic cardiomyopathy 2 trials · 86 incl. sub-types
40 sub-types
- Myotonic dystrophy type 1 45 trials Sub-types →
- Noonan syndrome and Noonan-related syndrome 1 trial · 29 incl. sub-types Sub-types →
- Beckwith-Wiedemann syndrome 6 trials Sub-types →
- 46,XY complete gonadal dysgenesis 0 trials · 1 incl. sub-types Sub-types →
- Dilated cardiomyopathy 1C 1 trial
- Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency 1 trial
- Multiple acyl-CoA dehydrogenase deficiency 1 trial Sub-types →
- Very long chain acyl-CoA dehydrogenase deficiency 1 trial
- Cardiomyopathy, familial hypertrophic 27 0 trials
- Cardiomyopathy, familial hypertrophic, 23, with or without ventricular noncompaction 0 trials
- Cardiomyopathy, familial hypertrophic, 28 0 trials
- Cardiomyopathy, familial hypertrophic, 29, with polyglucosan bodies 0 trials
- Cardiomyopathy, familial hypertrophic, 30, atrial 0 trials
- Cardiomyopathy, familial hypertrophic, 31 0 trials
- Cardiomyopathy, familial restrictive, 5 0 trials
- Cardiomyopathy-hypotonia-lactic acidosis syndrome 0 trials
- Dilated cardiomyopathy 1KK 0 trials
- Hypertrophic cardiomyopathy 1 0 trials
- Hypertrophic cardiomyopathy 10 0 trials
- Hypertrophic cardiomyopathy 11 0 trials
- Hypertrophic cardiomyopathy 12 0 trials
- Hypertrophic cardiomyopathy 13 0 trials
- Hypertrophic cardiomyopathy 14 0 trials
- Hypertrophic cardiomyopathy 15 0 trials
- Hypertrophic cardiomyopathy 16 0 trials
- Hypertrophic cardiomyopathy 17 0 trials
- Hypertrophic cardiomyopathy 18 0 trials
- Hypertrophic cardiomyopathy 19 0 trials
- Hypertrophic cardiomyopathy 2 0 trials
- Hypertrophic cardiomyopathy 20 0 trials
- Hypertrophic cardiomyopathy 21 0 trials
- Hypertrophic cardiomyopathy 25 0 trials
- Hypertrophic cardiomyopathy 26 0 trials
- Hypertrophic cardiomyopathy 3 0 trials
- Hypertrophic cardiomyopathy 4 0 trials
- Hypertrophic cardiomyopathy 6 0 trials
- Hypertrophic cardiomyopathy 7 0 trials
- Hypertrophic cardiomyopathy 8 0 trials
- Hypertrophic cardiomyopathy 9 0 trials
- Long chain acyl-CoA dehydrogenase deficiency 0 trials
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Familial restrictive cardiomyopathy 0 trials · 62 incl. sub-types
10 sub-types
- Glycogen storage disease II 31 trials · 41 incl. sub-types Sub-types →
- Gaucher disease type I 12 trials
- ATTRV122I amyloidosis 7 trials
- Atrial standstill 1 trial Sub-types →
- Idiopathic hypereosinophilic syndrome 1 trial Sub-types →
- Cardiomyopathy, familial restrictive, 1 0 trials
- Cardiomyopathy, familial restrictive, 2 0 trials
- Cardiomyopathy, familial restrictive, 3 0 trials
- Cardiomyopathy, familial restrictive, 6 0 trials
- Dilated cardiomyopathy 1KK 0 trials
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Familial dilated cardiomyopathy 7 trials · 61 incl. sub-types
29 sub-types
- Leber hereditary optic neuropathy 18 trials Sub-types →
- Familial isolated dilated cardiomyopathy 0 trials · 11 incl. sub-types Sub-types →
- Barth syndrome 5 trials
- Kearns-Sayre syndrome 5 trials
- Autosomal recessive limb-girdle muscular dystrophy type 2E 5 trials
- Emery-Dreifuss muscular dystrophy 2 trials · 4 incl. sub-types Sub-types →
- Autosomal recessive limb-girdle muscular dystrophy type 2C 4 trials
- Symptomatic form of muscular dystrophy of Duchenne and Becker in female carriers 4 trials
- Autosomal recessive limb-girdle muscular dystrophy type 2D 3 trials
- Histiocytoid cardiomyopathy 3 trials Sub-types →
- Autosomal recessive limb-girdle muscular dystrophy type 2F 2 trials
- PGM1-congenital disorder of glycosylation 1 trial
- Autosomal recessive limb-girdle muscular dystrophy type 2M 1 trial
- Autosomal recessive limb-girdle muscular dystrophy type 2W 1 trial
- Early-onset myopathy with fatal cardiomyopathy 1 trial
- DK1-congenital disorder of glycosylation 0 trials
- Cardiomyopathy, dilated, 100 0 trials
- Cardiomyopathy, dilated, 1LL 0 trials
- Cardiomyopathy, dilated, 1MM 0 trials
- Cardiomyopathy, dilated, 1QQ 0 trials
- Cardiomyopathy, dilated, 2I 0 trials
- Cardiomyopathy, dilated, 2K 0 trials
- Cardiomyopathy, dilated, 2M 0 trials
- Cardiomyopathy, dilated, 2j 0 trials
- Cardiomyopathy, dilated, 2l 0 trials
- Cardiomyopathy, dilated, 3C 0 trials
- Dilated cardiomyopathy 1J 0 trials
- Hypertrophic cardiomyopathy 25 0 trials
- Myofibrillar myopathy 1 0 trials
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Familial isolated arrhythmogenic right ventricular dysplasia 0 trials · 10 incl. sub-types
16 sub-types
- Arrhythmogenic right ventricular dysplasia 9 5 trials
- Arrhythmogenic right ventricular dysplasia 1 3 trials
- Familial isolated arrhythmogenic ventricular dysplasia, left dominant form 3 trials
- Catecholaminergic polymorphic ventricular tachycardia 1 2 trials
- Arrhythmogenic right ventricular dysplasia 10 0 trials
- Arrhythmogenic right ventricular dysplasia 11 0 trials
- Arrhythmogenic right ventricular dysplasia 12 0 trials
- Arrhythmogenic right ventricular dysplasia 13 0 trials
- Arrhythmogenic right ventricular dysplasia 3 0 trials
- Arrhythmogenic right ventricular dysplasia 4 0 trials
- Arrhythmogenic right ventricular dysplasia 5 0 trials
- Arrhythmogenic right ventricular dysplasia 6 0 trials
- Arrhythmogenic right ventricular dysplasia 8 0 trials
- Arrhythmogenic right ventricular dysplasia, familial, 14 0 trials
- Familial isolated arrhythmogenic ventricular dysplasia, biventricular form 0 trials
- Familial isolated arrhythmogenic ventricular dysplasia, right dominant form 0 trials
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Left ventricular noncompaction 3 trials · 4 incl. sub-types
13 sub-types
- Dilated cardiomyopathy 1C 1 trial
- Dilated cardiomyopathy 1D 0 trials
- Dilated cardiomyopathy 1R 0 trials
- Dilated cardiomyopathy 1S 0 trials
- Dilated cardiomyopathy 1Y 0 trials
- Left ventricular noncompaction 1 0 trials
- Left ventricular noncompaction 10 0 trials
- Left ventricular noncompaction 2 0 trials
- Left ventricular noncompaction 4 0 trials
- Left ventricular noncompaction 5 0 trials
- Left ventricular noncompaction 7 0 trials
- Left ventricular noncompaction 8 0 trials
- Left ventricular noncompaction 9 0 trials
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PRKAG2-related cardiomyopathy 2 trials · 4 incl. sub-types
3 sub-types
- Wolff-Parkinson-White syndrome 3 trials
- Hypertrophic cardiomyopathy 6 0 trials
- Lethal congenital glycogen storage disease of heart 0 trials
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Naxos disease 0 trials
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4 sub-types
- Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 1 0 trials
- Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 2 0 trials
- Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 3 0 trials
- Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 4 0 trials
Most studied deeper sub-types
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New cancer pill shows early promise, but trial halted
Disease control Stopped earlyThis early-stage trial tested an oral drug called TNO155, alone or with another drug (nazartinib), in 227 adults with advanced solid tumors like lung cancer, melanoma, and head/neck cancer. The main goal was to check safety and find the right dose. The study was terminated early,…
Phase 1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Heart drug study halted early: what we know
Disease control Stopped earlyThis study tested an experimental drug called CRD-4730 in people with a rare inherited heart rhythm disorder (CPVT) that can cause dangerous fast heartbeats. Seven adults received two different doses of the drug and a placebo to check safety and how the body processes it. The stu…
Phase 2 • Sponsor: Cardurion Pharmaceuticals, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Experimental gene therapy for rare muscle disease shows early promise but study halted
Disease control Stopped earlyThis study tested a gene therapy called SRP-9003 for people with limb-girdle muscular dystrophy type 2E (LGMD2E), a rare genetic disease that causes muscle weakness. The treatment aimed to deliver a working gene to muscle cells to help them produce a missing protein. Only 6 peopl…
Phase 1/2 • Sponsor: Sarepta Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Pompe disease drug trial halted after just 3 patients
Disease control Stopped earlyThis study tested an oral drug called duvoglustat in adults with Pompe disease, a rare genetic disorder that causes muscle weakness. Only 3 people took part, and the study was stopped early. Researchers looked at safety and whether the drug could improve walking distance and othe…
Phase 2 • Sponsor: Amicus Therapeutics • Aim: Disease control
Last updated Jun 26, 2026 16:43 UTC
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Experimental gene therapy tested for rare muscular dystrophy
Disease control Stopped earlyThis early-stage trial tested a gene therapy called SRP-9004 in just 4 people with limb girdle muscular dystrophy type 2D/R3, a rare muscle-weakening disease. The main goal was to check safety, not effectiveness. The study was terminated early, so results are limited.
Phase 1 • Sponsor: Sarepta Therapeutics, Inc. • Aim: Disease control
Last updated Jun 26, 2026 13:47 UTC
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Scientists dive into cells to unravel costello Syndrome's secrets
Knowledge-focused Stopped earlyThis study collects small skin samples from children aged 2 to 17 with Costello syndrome or a related condition. Researchers will analyze the cells to understand how a mutation in the HRAS gene affects energy use and mitochondria. The goal is to learn more about the disease's und…
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Hidden heart condition: study seeks to uncover missed diagnosis in heart failure patients
Knowledge-focused Stopped earlyThis study aims to find out how common transthyretin amyloidosis cardiomyopathy (ATTR-CM) is in Russian patients with a certain type of heart failure. Researchers will review medical records and then invite some patients for extra heart tests to confirm or rule out ATTR-CM. The g…
Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:47 UTC