Familial cardiomyopathy
MONDO:0005217An instance of cardiomyopathy that is caused by an inherited modification of the individual's genome.
Also known as: hereditary cardiomyopathy
226 clinical trials for this condition and its sub-types, 2 tagged with Familial cardiomyopathy itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Familial cardiomyopathy
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Familial hypertrophic cardiomyopathy 2 trials · 86 incl. sub-types
40 sub-types
- Myotonic dystrophy type 1 45 trials Sub-types →
- Noonan syndrome and Noonan-related syndrome 1 trial · 29 incl. sub-types Sub-types →
- Beckwith-Wiedemann syndrome 6 trials Sub-types →
- 46,XY complete gonadal dysgenesis 0 trials · 1 incl. sub-types Sub-types →
- Dilated cardiomyopathy 1C 1 trial
- Long chain 3-hydroxyacyl-CoA dehydrogenase deficiency 1 trial
- Multiple acyl-CoA dehydrogenase deficiency 1 trial Sub-types →
- Very long chain acyl-CoA dehydrogenase deficiency 1 trial
- Cardiomyopathy, familial hypertrophic 27 0 trials
- Cardiomyopathy, familial hypertrophic, 23, with or without ventricular noncompaction 0 trials
- Cardiomyopathy, familial hypertrophic, 28 0 trials
- Cardiomyopathy, familial hypertrophic, 29, with polyglucosan bodies 0 trials
- Cardiomyopathy, familial hypertrophic, 30, atrial 0 trials
- Cardiomyopathy, familial hypertrophic, 31 0 trials
- Cardiomyopathy, familial restrictive, 5 0 trials
- Cardiomyopathy-hypotonia-lactic acidosis syndrome 0 trials
- Dilated cardiomyopathy 1KK 0 trials
- Hypertrophic cardiomyopathy 1 0 trials
- Hypertrophic cardiomyopathy 10 0 trials
- Hypertrophic cardiomyopathy 11 0 trials
- Hypertrophic cardiomyopathy 12 0 trials
- Hypertrophic cardiomyopathy 13 0 trials
- Hypertrophic cardiomyopathy 14 0 trials
- Hypertrophic cardiomyopathy 15 0 trials
- Hypertrophic cardiomyopathy 16 0 trials
- Hypertrophic cardiomyopathy 17 0 trials
- Hypertrophic cardiomyopathy 18 0 trials
- Hypertrophic cardiomyopathy 19 0 trials
- Hypertrophic cardiomyopathy 2 0 trials
- Hypertrophic cardiomyopathy 20 0 trials
- Hypertrophic cardiomyopathy 21 0 trials
- Hypertrophic cardiomyopathy 25 0 trials
- Hypertrophic cardiomyopathy 26 0 trials
- Hypertrophic cardiomyopathy 3 0 trials
- Hypertrophic cardiomyopathy 4 0 trials
- Hypertrophic cardiomyopathy 6 0 trials
- Hypertrophic cardiomyopathy 7 0 trials
- Hypertrophic cardiomyopathy 8 0 trials
- Hypertrophic cardiomyopathy 9 0 trials
- Long chain acyl-CoA dehydrogenase deficiency 0 trials
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Familial restrictive cardiomyopathy 0 trials · 62 incl. sub-types
10 sub-types
- Glycogen storage disease II 31 trials · 41 incl. sub-types Sub-types →
- Gaucher disease type I 12 trials
- ATTRV122I amyloidosis 7 trials
- Atrial standstill 1 trial Sub-types →
- Idiopathic hypereosinophilic syndrome 1 trial Sub-types →
- Cardiomyopathy, familial restrictive, 1 0 trials
- Cardiomyopathy, familial restrictive, 2 0 trials
- Cardiomyopathy, familial restrictive, 3 0 trials
- Cardiomyopathy, familial restrictive, 6 0 trials
- Dilated cardiomyopathy 1KK 0 trials
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Familial dilated cardiomyopathy 7 trials · 61 incl. sub-types
29 sub-types
- Leber hereditary optic neuropathy 18 trials Sub-types →
- Familial isolated dilated cardiomyopathy 0 trials · 11 incl. sub-types Sub-types →
- Barth syndrome 5 trials
- Kearns-Sayre syndrome 5 trials
- Autosomal recessive limb-girdle muscular dystrophy type 2E 5 trials
- Emery-Dreifuss muscular dystrophy 2 trials · 4 incl. sub-types Sub-types →
- Autosomal recessive limb-girdle muscular dystrophy type 2C 4 trials
- Symptomatic form of muscular dystrophy of Duchenne and Becker in female carriers 4 trials
- Autosomal recessive limb-girdle muscular dystrophy type 2D 3 trials
- Histiocytoid cardiomyopathy 3 trials Sub-types →
- Autosomal recessive limb-girdle muscular dystrophy type 2F 2 trials
- PGM1-congenital disorder of glycosylation 1 trial
- Autosomal recessive limb-girdle muscular dystrophy type 2M 1 trial
- Autosomal recessive limb-girdle muscular dystrophy type 2W 1 trial
- Early-onset myopathy with fatal cardiomyopathy 1 trial
- DK1-congenital disorder of glycosylation 0 trials
- Cardiomyopathy, dilated, 100 0 trials
- Cardiomyopathy, dilated, 1LL 0 trials
- Cardiomyopathy, dilated, 1MM 0 trials
- Cardiomyopathy, dilated, 1QQ 0 trials
- Cardiomyopathy, dilated, 2I 0 trials
- Cardiomyopathy, dilated, 2K 0 trials
- Cardiomyopathy, dilated, 2M 0 trials
- Cardiomyopathy, dilated, 2j 0 trials
- Cardiomyopathy, dilated, 2l 0 trials
- Cardiomyopathy, dilated, 3C 0 trials
- Dilated cardiomyopathy 1J 0 trials
- Hypertrophic cardiomyopathy 25 0 trials
- Myofibrillar myopathy 1 0 trials
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Familial isolated arrhythmogenic right ventricular dysplasia 0 trials · 10 incl. sub-types
16 sub-types
- Arrhythmogenic right ventricular dysplasia 9 5 trials
- Arrhythmogenic right ventricular dysplasia 1 3 trials
- Familial isolated arrhythmogenic ventricular dysplasia, left dominant form 3 trials
- Catecholaminergic polymorphic ventricular tachycardia 1 2 trials
- Arrhythmogenic right ventricular dysplasia 10 0 trials
- Arrhythmogenic right ventricular dysplasia 11 0 trials
- Arrhythmogenic right ventricular dysplasia 12 0 trials
- Arrhythmogenic right ventricular dysplasia 13 0 trials
- Arrhythmogenic right ventricular dysplasia 3 0 trials
- Arrhythmogenic right ventricular dysplasia 4 0 trials
- Arrhythmogenic right ventricular dysplasia 5 0 trials
- Arrhythmogenic right ventricular dysplasia 6 0 trials
- Arrhythmogenic right ventricular dysplasia 8 0 trials
- Arrhythmogenic right ventricular dysplasia, familial, 14 0 trials
- Familial isolated arrhythmogenic ventricular dysplasia, biventricular form 0 trials
- Familial isolated arrhythmogenic ventricular dysplasia, right dominant form 0 trials
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Left ventricular noncompaction 3 trials · 4 incl. sub-types
13 sub-types
- Dilated cardiomyopathy 1C 1 trial
- Dilated cardiomyopathy 1D 0 trials
- Dilated cardiomyopathy 1R 0 trials
- Dilated cardiomyopathy 1S 0 trials
- Dilated cardiomyopathy 1Y 0 trials
- Left ventricular noncompaction 1 0 trials
- Left ventricular noncompaction 10 0 trials
- Left ventricular noncompaction 2 0 trials
- Left ventricular noncompaction 4 0 trials
- Left ventricular noncompaction 5 0 trials
- Left ventricular noncompaction 7 0 trials
- Left ventricular noncompaction 8 0 trials
- Left ventricular noncompaction 9 0 trials
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PRKAG2-related cardiomyopathy 2 trials · 4 incl. sub-types
3 sub-types
- Wolff-Parkinson-White syndrome 3 trials
- Hypertrophic cardiomyopathy 6 0 trials
- Lethal congenital glycogen storage disease of heart 0 trials
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Naxos disease 0 trials
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4 sub-types
- Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 1 0 trials
- Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 2 0 trials
- Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 3 0 trials
- Cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 4 0 trials
Most studied deeper sub-types
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Cancer drug tested against deadly infant heart disease
Disease control Not yet recruitingResearchers are testing whether trametinib, an FDA-approved cancer drug, can help infants with RASopathies who have a severe, life-threatening heart condition called hypertrophic cardiomyopathy. The trial enrolls about 25 babies with a confirmed genetic diagnosis. Participants re…
Phase 3 • Sponsor: Carelon Research • Aim: Disease control
Last updated Sep 16, 2026 00:00 UTC
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Can an oral pill ease breathing and muscle weakness in pompe disease?
Disease control Not yet recruitingThis early-stage trial is testing an experimental oral medication called S-606001 in adults with late-onset Pompe disease, a condition that causes progressive muscle weakness and breathing problems. The main goal is to see if the drug is safe and tolerable. Researchers will also …
Phase 1 • Sponsor: Shionogi • Aim: Disease control
Last updated Aug 28, 2026 00:00 UTC
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Can an oral pill boost muscle strength in pompe disease?
Disease control Not yet recruitingThis study tests the long-term safety and effectiveness of an experimental oral drug called S-606001 in adults with late-onset Pompe disease, a genetic condition that causes progressive muscle weakness. Participants who completed a prior S-606001 study can join, and they will rec…
Phase 2 • Sponsor: Shionogi • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Can a simple muscle exercise improve erectile function in men with low testosterone?
Disease control Not yet recruitingThis study tests whether pelvic floor muscle training (PFMT) with a handheld biofeedback device can improve erectile function and sexual quality of life in men with functional hypogonadism (low testosterone) and erectile dysfunction. Participants are randomly assigned to PFMT wit…
Sponsor: Poznan University of Physical Education • Aim: Disease control
Last updated Jul 09, 2026 00:00 UTC
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Sugar supplement shows promise for rare disease in new trial
Disease control Not yet recruitingThis phase 2b trial tests AVTX-801, a D-galactose supplement, in 8 adults with PGM1-CDG, a rare genetic disorder affecting sugar metabolism. Participants currently on D-galactose will receive either the study drug or a placebo to see if it reduces disease-related events like low …
Phase 2 • Sponsor: Eva Morava-Kozicz • Aim: Disease control
Last updated Jun 27, 2026 11:01 UTC
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Could vitamin B3 save sight in rare genetic blindness?
Disease control Not yet recruitingThis early study tests whether high-dose vitamin B3 (nicotinamide) can help preserve or improve vision in people with Leber's hereditary optic neuropathy (LHON), a rare genetic disease that causes sudden vision loss. Researchers will give 13 participants 2 grams of vitamin B3 dai…
Phase 1 • Sponsor: University Hospital, Angers • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Could a common blood pressure pill ease muscle stiffness? early trial launches
Symptom relief Not yet recruitingThis early-stage trial tests amlodipine, a calcium channel blocker used for high blood pressure, in 20 adults with myotonic dystrophy type 1. The goal is to see if the drug is safe and can improve muscle strength, reduce stiffness, and help with daily function. All participants w…
Phase 1 • Sponsor: University of Rochester • Aim: Symptom relief
Last updated Jun 27, 2026 08:03 UTC
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Could you help scientists unlock genetic cancer secrets?
Knowledge-focused Not yet recruitingThis study screens up to 1,000 people with personal or family histories of certain cancers to see if they qualify for ongoing genetics research at the National Cancer Institute. Participants fill out a 15-20 minute online survey about their health and family history. No treatment…
Sponsor: National Cancer Institute (NCI) • Aim: Knowledge-focused
Last updated Sep 21, 2026 19:00 UTC
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Can watching the course of myotonic dystrophy unlock better care?
Knowledge-focused Not yet recruitingThis study follows 100 adults with myotonic dystrophy (types 1 or 2) for two years to understand how muscle stiffness, daily function, and heart health change over time. Researchers will look back at up to 18 months of past medical records and then track participants with clinic …
Sponsor: Lupin Ltd. • Aim: Knowledge-focused
Last updated Jul 30, 2026 00:00 UTC
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Scientists investigate hidden genetic patterns in rare childhood disorders
Knowledge-focused Not yet recruitingThis study aims to better understand a condition called multilocus imprinting disorder (MLID), where multiple genes are affected by abnormal chemical marks. Researchers will test a new technique to detect these marks in 96 people, including those with known imprinting disorders a…
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:01 UTC
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Heart ablation study aims to improve arrhythmia treatment
Knowledge-focused Not yet recruitingThis study looks back at medical records of 220 patients who had a procedure called radiofrequency ablation for heart rhythm issues. The goal is to compare how well the procedure works for two types of abnormal heart connections. Researchers hope to find which type is easier to t…
Sponsor: IRCCS Ospedale San Raffaele • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:08 UTC
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New registry aims to improve care for muscular dystrophy patients
Knowledge-focused Not yet recruitingThis study is creating a registry for people with Duchenne and Becker muscular dystrophy, as well as symptomatic female carriers. The goal is to collect health data and quality-of-life information to monitor how new therapies work in real-world settings. Up to 1,500 participants …
Sponsor: Dr. Andreas Ziegler • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:05 UTC
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New study aims to predict bleeding dangers in noonan syndrome patients
Knowledge-focused Not yet recruitingThis study looks at why people with Noonan syndrome often bleed easily, especially from the skin, mouth, or nose. Researchers will compare a simple questionnaire about bleeding history with blood tests in 100 patients. The goal is to find better ways to predict serious bleeding, …
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:00 UTC