Essential tremor

This study compares two ways of giving Botox injections to treat voice tremor, a condition that causes a shaky voice. About 30 adults with essential voice tremor will receive either a standard injection guided by muscle signals or a newer injection into a different part of the vo…

This small pilot study will test whether a non-invasive electrical stimulation technique called tTIS can reduce tremors in people with essential tremor. Six adults who are already candidates for a standard treatment (focused ultrasound) will receive tTIS to a deep brain area invo…

This study tests whether a precise beam of ultrasound directed at a small part of the brain (the dentate nucleus) can reduce tremor. First, 30 healthy volunteers will have their hand tremor measured during ultrasound to find the best settings. Then, 30 people with essential tremo…

This study tests if low-intensity focused ultrasound (LIFU) can safely reduce tremors and improve quality of life in people with essential tremor. Twenty adults with hard-to-treat tremors will receive both real LIFU and a fake (sham) treatment in separate sessions to compare effe…

This study tests whether using brain images to program deep brain stimulation (DBS) devices works better than the usual method for reducing hand tremors in people with essential tremor. Twenty adults who already have DBS electrodes in their brain will try both programming approac…

This study looks at whether new ways of programming deep brain stimulation (DBS) can improve tremor control in adults with essential tremor who stopped responding to standard DBS. Five participants will try six different stimulation settings and use one at home for three months. …

This study will look at 800 patients who had aortic surgery to understand why some develop dangerous blood clots inside the repaired artery. Researchers want to find out how common these clots are, what puts patients at risk, and how they affect recovery. The goal is to improve c…