Epidemic louse-borne typhus
MONDO:0019362A gram-negative bacterial infection caused by Rickettsia prowazekii. It is spread by lice infected with the bacteria. Signs and symptoms include sudden headache, generalized muscle pain, malaise, and macular skin lesions. The infection may affect the central nervous system causing encephalitis.
Also known as: typhus, epidemic louse-borne typhus, epidemic typhus, epidemic typhus fever
9 clinical trials for this condition and its sub-types.
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Broader categories
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New antibiotic cocktail aimed at Drug-Resistant infections in babies
Disease control Recruiting nowThis study tests a combination of two antibiotics, aztreonam and avibactam, in newborns and infants up to 9 months old who have serious infections caused by gram-negative bacteria. The trial has two parts: one to see how a single dose moves through the body, and another to test m…
Phase: PHASE2 • Sponsor: Pfizer • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Double antibiotic attack: could a Two-Drug combo beat severe infections faster?
Disease control Recruiting nowThis study tests whether adding a second antibiotic (fosfomycin) to the standard antibiotic (ceftazidime) helps people with severe gram-negative infections recover faster. About 100 hospitalized adults will be randomly assigned to get either the combo or the standard drug plus a …
Phase: PHASE3 • Sponsor: Angela HUTTNER • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Scientists hunt Tick-Borne germs to unlock disease patterns
Knowledge-focused Recruiting nowThis study is observing up to 2,000 people in Russia who have or may have rickettsiosis, a tick-borne illness. Researchers will collect leftover blood or swab samples from standard tests to identify the specific germ causing the infection. They will then compare the germ type wit…
Sponsor: Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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Real-World watch: is zavicefta safe for tough infections?
Knowledge-focused Recruiting nowThis study observes 600 patients in Korea who receive Zavicefta for complicated abdominal or urinary tract infections or hospital-acquired pneumonia. Researchers track side effects and how well the drug works. It is required by Korean regulators to ensure the drug's safety after …
Sponsor: Pfizer • Aim: Knowledge-focused
Last updated Jun 26, 2026 12:53 UTC