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EPHB4-associated vascular malformation spectrum

MONDO:0700080

Any vascular malformation in which the cause of the disease is a variation in the EPHB4 gene.

6 clinical trials for this condition and its sub-types.

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Sub-types

Capillary malformation-arteriovenous malformation 2 (0) Lymphatic malformation 7 (0)

Broader categories

Cardiovascular disorder (1051) Disease (680) Hereditary disease (176) Vascular disorder (135) Vascular malformation (31) Human disease (14) Disease of genetic or genomic mechanism (2) Disease by body system or component (0) Disease by etiologic mechanism (0)

Not yet recruiting 2 Not yet finished but already full! 1 Completed 2 Terminated 1

Electric pulses may boost a drug's power against painful vascular malformations

Symptom relief ENROLLING_BY_INVITATION

Slow-flow vascular malformations — abnormal clusters of veins, capillaries, or lymph vessels — can cause pain, swelling, and appearance concerns. This study follows 60 children and adults who receive bleomycin electrosclerotherapy (BEST), a procedure that injects the drug bleomyc…

Sponsor: Rigshospitalet, Denmark • Aim: Symptom relief

Last updated Jul 24, 2026 00:00 UTC