EPHB4-associated vascular malformation spectrum
MONDO:0700080Any vascular malformation in which the cause of the disease is a variation in the EPHB4 gene.
6 clinical trials for this condition and its sub-types.
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Broader categories
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Could a transplant drug shrink Children's birthmarks?
Disease control CompletedThis study tested the drug sirolimus (rapamycin) in 63 children aged 6 to 18 with large, complicated slow-flow vascular malformations (abnormal blood or lymph vessels). Each child had an observation period followed by 4 to 8 months of sirolimus treatment. The main goal was to see…
Phase: PHASE2 • Sponsor: University Hospital, Tours • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New contrast dye aims to sharpen MRI images of body lesions
Diagnosis CompletedThis study tests a new contrast agent called HRS-9231 for MRI scans of body parts (excluding the brain and spine). The goal is to see if it makes abnormal blood vessels or lesions show up as clearly as a standard contrast agent. About 309 adults who already need a contrast MRI ar…
Phase: PHASE3 • Sponsor: Shanghai Shengdi Pharmaceutical Co., Ltd • Aim: Diagnosis
Last updated Jul 02, 2026 00:00 UTC