Drug shows promise for shrinking painful vascular birth defects in kids
NCT ID NCT02509468
First seen Jan 05, 2026 · Last updated May 15, 2026 · Updated 24 times
Summary
This study tested the drug sirolimus in 63 children aged 6 to 18 with large, complicated slow-flow vascular malformations (abnormal clusters of blood or lymph vessels). The goal was to see if sirolimus could shrink the malformations and ease symptoms like pain, bleeding, and swelling. Children were observed for a period, then treated with sirolimus for 12 months, with MRI scans used to measure changes in size.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Consultations externes de Dermatologie, Hôpital Clocheville, CHU Tours
Tours, 37000, France
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Explorations Médecine Vasculaire Hôpital A. Michallon, CHU de Grenoble
Grenoble, 38700, France
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Service de Dermatologie, Hôpital Hôtel-Dieu, CHU Nantes
Nantes, 44000, France
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Service de Dermatologie, Hôpital Pontchaillou, CHU RENNES
Rennes, 35000, France
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Service de Dermatologie, Hôpital St Eloi, CHU Montpellier
Montpellier, 34000, France
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Service de Dermatologie, vénéréologie et cancérologie cutanée, Hôpital La Timone APHM
Marseille, 13000, France
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Service de dermatologie, APHP Necker
Paris, 75743, France
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Service de dermatologie, CHU Angers
Angers, 49933, France
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Service de dermatologie, CHU Nice
Nice, 06202, France
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Service de dermatologie, Hôpital Larrey, CHU Toulouse
Toulouse, 31059, France
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Service de dermatologie, Hôpital du Bocage, CHU Dijon
Dijon, 21079, France
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Service de radiologie Hôpital Femme-Mère-Enfant, Hospices Civils de Lyon
Lyon, 69000, France
Conditions
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