EPHB4-associated vascular malformation spectrum
MONDO:0700080Any vascular malformation in which the cause of the disease is a variation in the EPHB4 gene.
6 clinical trials for this condition and its sub-types.
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Broader categories
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Electric shocks boost drug to shrink blood vessel tangles
Disease control Not yet recruitingThis phase 2 trial tests a new treatment called bleomycin electrosclerotherapy (BEST) for low-flow vascular malformations—abnormal clusters of blood or lymph vessels. The approach combines an injected drug (bleomycin) with brief electrical pulses to make the drug work better. Res…
Phase: PHASE2 • Sponsor: Institute of Oncology Ljubljana • Aim: Disease control
Last updated Jun 27, 2026 12:37 UTC
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New hope for rare blood vessel disorders: everolimus trial launches
Disease control Not yet recruitingThis phase 2 trial tests the drug everolimus in 67 people with vascular anomalies (abnormal blood vessels) that haven't responded to standard treatments. The goal is to shrink the lesions and improve symptoms. Participants take everolimus daily for 6 months, with doses adjusted b…
Phase: PHASE2 • Sponsor: Yonsei University • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC