Endomyocardial fibrosis
MONDO:0006746A disease characterized by fibrotic thickening of the endocardium, particularly the right and/or left inflow tracts. The disease often involves the atrioventricular valves, leading to valvular regurgitaion. It most commonly occurs in children living within 15 degrees of the equator.
Also known as: African endomyocardial fibrosis
22 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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MRI-Guided heart procedure aims to stop dangerous rhythms
Disease control CompletedThis study tested whether using cardiac MRI to guide ablation (a procedure that destroys small areas of heart tissue) can improve outcomes for people with ventricular tachycardia, a dangerous fast heart rhythm. 104 adults with structural heart disease were randomly assigned to on…
Phase: PHASE4 • Sponsor: Azienda Ospedaliero, Universitaria Pisana • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Blood pressure drug may shield hearts during breast cancer radiation
Prevention CompletedThis early-phase study tested whether losartan, a common blood pressure medication, could prevent early heart damage caused by radiation therapy in breast cancer patients. Five women with left-sided breast cancer who were scheduled for radiation took losartan. Researchers used he…
Phase: EARLY_PHASE1 • Sponsor: Massachusetts General Hospital • Aim: Prevention
Last updated Jun 27, 2026 12:04 UTC
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Small study probes ultrasound's ability to spot hidden heart scarring
Knowledge-focused CompletedThis study looked at 22 people with severe aortic stenosis who were scheduled for valve replacement. Before surgery, they had an ultrasound of the heart, and during surgery a tiny sample of heart muscle was taken to check for scarring (fibrosis). The goal was to see if ultrasound…
Sponsor: Norwegian University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:09 UTC
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MRI scans could help doctors decide the best time for heart valve surgery
Knowledge-focused CompletedThis study looked at 86 people with severe aortic valve stenosis who had valve replacement surgery. Researchers used special MRI scans to measure scarring in the heart muscle before and one year after surgery. The goal was to see if the scarring improves and whether MRI could hel…
Sponsor: Rigshospitalet, Denmark • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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New MRI technique spots hidden heart bleeding
Knowledge-focused CompletedThis study tested new MRI methods to detect bleeding inside the heart muscle after a heart attack. Researchers studied 14 patients to see if these scans could better identify damage that raises the risk of heart failure. The goal was to improve imaging, not to test a treatment.
Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:02 UTC