Ehlers-Danlos syndrome, hypermobility type
MONDO:0007523Ehlers-Danlos syndrome, hypermobility type (HT-EDS) is the most frequent form of EDS, a group of hereditary connective tissue diseases, and is characterized by joint hyperlaxity, mild skin hyperextensibility, tissue fragility and extra-musculoskeletal manifestations.
Also known as: EDS III, EDSHMB, Ehlers-Danlos syndrome type 3, Ehlers-Danlos syndrome type 3 (formerly), Ehlers-Danlos syndrome, hypermobile type, Ehlers-Danlos syndrome, hypermobility type, Ehlers-Danlos syndrome, type 3, Ehlers-Danlos syndrome, type III
18 clinical trials for this condition and its sub-types.
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Could online pilates ease pain for those with stretchy joints?
Symptom relief CompletedThis study investigates whether an online Pilates program designed for people with hypermobile Ehlers-Danlos syndrome or hypermobility spectrum disorder can reduce pain and improve function. Participants follow 25-minute guided videos three times a week for eight weeks. Researche…
Phase: NA • Sponsor: Clarkson University • Aim: Symptom relief
Last updated Jun 27, 2026 14:00 UTC
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Ear stimulation device shows promise for Ehlers-Danlos relief
Symptom relief CompletedThis study tested whether a small, at-home device that stimulates a nerve in the ear can improve symptoms like pain, fatigue, sleep, and mood in people with hypermobile Ehlers-Danlos syndrome (hEDS). Twenty-five adults with hEDS used the device daily for two weeks, with some rece…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Could a simple ear device ease hEDS symptoms?
Symptom relief CompletedThis study tested a wearable device that delivers mild electrical stimulation to the ear in 30 adults with hypermobile Ehlers-Danlos syndrome (hEDS). The goal was to see if it could improve quality of life by reducing symptoms like pain, fatigue, sleep problems, and anxiety. Part…
Phase: NA • Sponsor: Medical University of South Carolina • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Could tight clothing and dance help EDS patients regain balance?
Symptom relief CompletedThis study tested whether wearing compression garments and doing specific physiotherapy exercises could improve balance and quality of life in people with hypermobile Ehlers-Danlos syndrome (hEDS). Forty patients with hEDS were followed for a year, first receiving standard care, …
Phase: NA • Sponsor: University Hospital, Caen • Aim: Symptom relief
Last updated Jun 27, 2026 12:03 UTC
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Could a special vest ease crippling joint pain in Ehlers-Danlos patients?
Symptom relief CompletedThis study tested whether a custom compression vest (SED CICATREX®) can reduce shoulder pain and improve stability in adults with hypermobile Ehlers-Danlos syndrome. 48 participants wore the vest for 4 weeks, then went without it for 4 weeks. Researchers measured muscle strength,…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Gene sequencing uncovers mysterious fetal malformations
Knowledge-focused CompletedThis study tested whether a powerful DNA test called high-throughput exome sequencing can find genetic causes of multiple birth defects in fetuses when standard exams fail. Researchers studied 100 fetuses with at least two malformations and no prior diagnosis. They compared the n…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Speedy gene test aims to give answers on birth defects in just 7 days
Knowledge-focused CompletedThis study tested whether a fast type of genetic test called rapid genome sequencing can find the cause of birth defects seen on ultrasound more quickly than current methods. Researchers included 184 pregnancies with certain ultrasound findings. The goal was to see if results cou…
Sponsor: Centre Hospitalier Universitaire Dijon • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:00 UTC