Drug-induced liver injury
MONDO:0005359A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to acute liver failure, caused by drugs, drug metabolites, and chemicals from the environment.
Also known as: drug induced hepatotoxicity, drug-induced disorder of liver
23 clinical trials for this condition and its sub-types.
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Broader categories
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Could a new drug combo prevent liver failure after tylenol overdose?
Disease control TerminatedThis study tested whether adding fomepizole to the standard treatment (N-acetylcysteine) could better protect the liver in people who took too much acetaminophen (Tylenol). The trial included 29 adults and children aged 10 and older who were at high risk for liver injury. The goa…
Phase: PHASE2 • Sponsor: Richard Dart, MD, PhD • Aim: Disease control
Last updated Jun 27, 2026 07:59 UTC
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Heart drug digoxin tested for alcoholic hepatitis – early trial halted
Disease control TerminatedThis small, early-phase study tested whether the heart medication digoxin could reduce inflammation in people with severe alcohol-associated hepatitis. 23 participants were randomly assigned to receive intravenous digoxin or no digoxin for up to 28 days. The trial was terminated …
Phase: PHASE2 • Sponsor: Yale University • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Herbal medicine safety under the microscope in korean hospitals
Knowledge-focused TerminatedThis study observed women aged 19–80 who were hospitalized for at least two weeks and taking herbal medicines. Researchers tracked liver and kidney function through regular blood tests to see if any injuries occurred. The goal was to better understand the safety profile of these …
Sponsor: Korea Institute of Oriental Medicine • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:21 UTC