Drug-induced liver injury
MONDO:0005359A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to acute liver failure, caused by drugs, drug metabolites, and chemicals from the environment.
Also known as: drug induced hepatotoxicity, drug-induced disorder of liver
23 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Blood cancer patients may get liver protection from common drug
Disease control Not yet recruitingThis real-world study looks at whether polyene phosphatidylcholine injection can prevent or treat drug-induced liver injury in adults with blood cancers like leukemia and lymphoma. Researchers will review medical records of 1,000 patients to see how well the drug works and if it …
Sponsor: Institute of Hematology & Blood Diseases Hospital, China • Aim: Disease control
Last updated Jun 27, 2026 11:02 UTC
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SAMe supplement may shield liver from chemo harm
Prevention Not yet recruitingThis study tests whether taking S-adenosylmethionine (SAMe), a natural supplement, can prevent liver injury caused by the chemotherapy drug oxaliplatin. About 30 adults with colorectal cancer that has spread to the liver will take SAMe pills daily for 3-6 months alongside their c…
Phase: PHASE2 • Sponsor: Cedars-Sinai Medical Center • Aim: Prevention
Last updated Jun 27, 2026 12:29 UTC
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800-Patient study aims to unlock secrets of autoimmune liver disease
Knowledge-focused Not yet recruitingThis French study will collect medical data and biological samples from 800 people with autoimmune liver diseases. Researchers hope to identify new markers that explain why some patients respond well to treatment while others do not. The goal is to better understand the immune me…
Sponsor: Nantes University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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TB drug liver risk under the microscope
Knowledge-focused Not yet recruitingThis study will track 220 adults being treated for tuberculosis (TB) or latent TB with the drug isoniazid. Researchers want to see how often the drug causes liver injury and what factors make it more likely. They will also look at how doctors manage this side effect in real-world…
Sponsor: ASST Fatebenefratelli Sacco • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC