Drug dependence
MONDO:0005303Drug dependence - replaced the term "drug addiction" and is defined as a state, psychic and sometimes also physical, resulting from the interaction between a living organism and a drug, characterized by behavioral and other responses that always include a compulsion to take the drug on a continuous or periodic basis in order to experience its psychic effects, and sometimes to avoid the discomfort of its absence. Tolerance may or may not be present. A person may be dependent on more than one drug.
Also known as: chemical dependence
1368 clinical trials for this condition and its sub-types, 14 tagged with Drug dependence itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
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Sub-types of Drug dependence
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Opiate dependence 545 trials
2 sub-types
- Heroin dependence 2 trials
- Morphine dependence 2 trials
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Nicotine dependence 412 trials
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Cannabis dependence 218 trials
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Methamphetamine dependence 63 trials
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Cocaine dependence 52 trials
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Alcohol dependence 44 trials
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Hallucinogen dependence 1 trial
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Alcohol and nicotine codependence 0 trials
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Barbiturate dependence 0 trials
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Phencyclidine abuse 0 trials
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AI city halls: could Robot-Run domes cure addiction and homelessness?
Disease control Not yet recruitingThis study will test whether living in a self-contained, AI-managed community (called a Microcity) can improve mental health and reduce addiction in adults with conditions like autism, ADHD, substance use disorders, and behavioral addictions. Up to 1 million participants will liv…
Sponsor: Veterans Recovery Network Inc. • Aim: Disease control
Last updated Sep 19, 2026 00:00 UTC
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Study to reveal how weather and streets impact homeless health
Knowledge-focused Not yet recruitingThis study looks at how environmental factors like heat, cold, and pollution affect wounds, mental health, and drug use in homeless people in Augsburg. Researchers will compare wound care from a mobile unit to a hospital clinic, and use saliva tests to check drug use. The goal is…
Sponsor: University Hospital Augsburg • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:06 UTC