Drug allergy

This study looked at whether the HPV vaccine works in girls aged 9 to 17 who are taking medicines that weaken their immune system, such as after an organ transplant or for diseases like lupus. The goal was to see if their bodies produce enough antibodies to protect against HPV. T…

This study looked at nearly 500 patients who had a paracetamol (acetaminophen) allergy test over 22 years. The goal was to find the smallest dose that triggers a reaction, so future tests can be shorter and safer. By analyzing past data, researchers hope to create a simplified te…

This study tested whether a standard allergy work-up can accurately identify people who were incorrectly labeled as allergic to penicillin. 155 adults with a suspected penicillin allergy went through testing, including a drug challenge to confirm if they were truly allergic. The …

This study looked at whether a blood test called flow cytometry can accurately diagnose allergic reactions to muscle relaxants given during anesthesia. Researchers tested 129 adults who had a suspected allergic reaction during a past surgery. The goal was to see if the test could…

This study tested whether giving full therapeutic doses of anaesthetics like propofol and ketamine can safely diagnose drug allergies in people who had a suspected allergic reaction during surgery. Fifty adult patients with a history of perioperative hypersensitivity underwent in…

This study tested three ways of giving the steroid dexamethasone to prevent allergic reactions from the chemotherapy drug paclitaxel in 90 women with breast or gynecologic cancer. One group took oral dexamethasone the night before and morning of treatment, another got it intraven…

This study tested whether children under 16 with a history of mild beta-lactam (like penicillin) allergies could safely take the drug again without first having skin tests. Researchers used a questionnaire to identify low-risk kids and then gave them an oral dose. The goal was to…

This study tested a digital decision support tool for doctors treating hospitalized patients who report a penicillin allergy. Most people who think they are allergic to penicillin are not actually allergic, but they often receive less effective antibiotics. The tool helps doctors…

This study looked at children aged 0-18 who had mild, delayed allergic reactions to beta-lactam antibiotics (like amoxicillin). Researchers compared short (1-4 days) and long (5-8 days) oral drug challenge tests to see if longer testing increased the growth of antibiotic-resistan…

This study tested a Turkish version of a questionnaire that measures how drug allergies in children affect their caregivers' quality of life. Researchers worked with 74 parents or guardians to see if the translated questions were reliable and accurate. The goal was to create a to…

This study collected blood, saliva, stool, urine, and skin samples from 19 people with unknown or poorly understood immune system problems. The goal was to learn how different parts of the immune system work together. No treatments or drugs were tested. Participants were followed…

This study looked at how two common seasickness drugs (scopolamine and meclizine) change inner ear balance tests in 54 healthy soldiers who get seasick. Researchers measured eye movements before and after taking the drugs to see if these tests could predict which drug works best …

This study looked at 20 years of data from over 1,200 patients to find the safest and most effective doses for drug provocation tests (DPTs) for beta-lactam allergies. Researchers analyzed past positive tests to create a new, simpler testing protocol. They will now test this new …