Diphtheria
MONDO:0005504A Gram-positive bacterial infection caused by Corynebacterium diphtheriae. It usually involves the oral cavity, pharynx, and nasal cavity. Patients develop pseudomembranes in the affected areas and manifest signs and symptoms of an upper respiratory infection. The diphtheria toxin may cause myocarditis, polyneuritis, and other systemic effects.
24 clinical trials for this condition and its sub-types.
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Broader categories
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New vaccine for moms could shield babies from whooping cough
⭐️ VACCINE ⭐️ Not yet recruitingThis study tests a new vaccine called TdaP2gen in 320 pregnant women in Thailand to see if it safely protects their babies from tetanus, diphtheria, and whooping cough. The vaccine is given during pregnancy, and researchers measure antibody levels in mothers and infants up to 18 …
Phase: PHASE4 • Sponsor: Chiang Mai University • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 13:01 UTC
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New vaccine trial aims to shield teens and adults from whooping cough
⭐️ VACCINE ⭐️ Not yet recruitingThis early-stage trial is testing a new combination vaccine that protects against whooping cough, diphtheria, and tetanus (Tdap) in people aged 10 and older. Researchers want to see if different doses are safe and trigger an immune response. The study involves 96 volunteers and c…
Phase: PHASE1 • Sponsor: Changchun BCHT Biotechnology Co. • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 12:00 UTC
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New Low-Dose tdap vaccine trial aims to boost protection with fewer side effects
⭐️ VACCINE ⭐️ Not yet recruitingThis study tests a new version of the Tdap vaccine (which protects against tetanus, diphtheria, and whooping cough) that has reduced antigens. The goal is to see if it is safe and triggers a strong immune response in people aged 6 and up. Around 660 volunteers will receive either…
Phase: PHASE1, PHASE2 • Sponsor: Institute of Medical Biology, Chinese Academy of Medical Sciences • Aim: ⭐️ VACCINE ⭐️
Last updated Jun 27, 2026 09:06 UTC
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Will a single DTP vaccine dose protect for a decade? study tracks antibodies
Knowledge-focused Not yet recruitingThis study follows 160 people who previously received a 5-component DTP vaccine (protecting against diphtheria, tetanus, and pertussis) to see how long their immune protection lasts. Blood samples are taken at 2.5, 5, and 10 years after vaccination to measure antibody levels. The…
Sponsor: CanSino Biologics Inc. • Aim: Knowledge-focused
Last updated Aug 06, 2026 00:00 UTC