New vaccine trial aims to shield teens and adults from whooping cough

NCT ID NCT07492303

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial is testing a new combination vaccine that protects against whooping cough, diphtheria, and tetanus (Tdap) in people aged 10 and older. Researchers want to see if different doses are safe and trigger an immune response. The study involves 96 volunteers and compares the vaccine to a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Tdap vaccine (acellular pertussis, diphtheria, tetanus combined)
What this could lead to
If successful, this could lead to a new, safe vaccine option to protect adolescents and adults from whooping cough, diphtheria, and tetanus.
What could go wrong
This is an early Phase 1 trial with only 96 participants, so it's too soon to know if the vaccine works. The main goal is safety, and unexpected side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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