Dialysis disequilibrium syndrome
MONDO:0975708A syndrome that occurs during or after hemodialysis, or rarely continuous renal replacement therapy, characterized by variable, primarily neurological symptoms including headache, nausea, blurred vision, restlessness, confusion, dizziness, muscle cramps, intraocular pressure and, in severe cases, seizures, somnolence, stupor, or coma.
32 clinical trials for this condition and its sub-types.
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Dialysis patients may straighten up with In-Chair exercise
Disease control Recruiting nowThis trial investigates whether a 12-week supervised exercise program, done during regular hemodialysis sessions, can improve postural problems like hunched back and forward head posture in adults with end-stage renal disease. Participants will be randomly assigned to either the …
Sponsor: Pardis Specialized Wellness Institute • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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Can adding urea to dialysis prevent dangerous brain swelling?
Disease control Recruiting nowThis study tests whether adding urea to the dialysis fluid can prevent dialysis disequilibrium syndrome — a set of neurological symptoms like headache, confusion, and seizures — in people with kidney failure who need urgent dialysis for severe electrolyte problems. Researchers wi…
Phase 1/2 • Sponsor: University of California, San Francisco • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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New dialysis filter aims to tame chronic inflammation
Disease control Recruiting nowThis study tests whether special filters (sorption technologies) can lower inflammation in people on long-term hemodialysis for kidney failure. About 60 adults with high inflammation levels will receive the filter during their regular dialysis sessions. The main goal is to see if…
Sponsor: Botkin Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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A helping hand for dialysis: can coaching reduce the emotional toll?
Symptom relief Recruiting nowThis study tests whether a 6-week nurse-led self-management program can reduce dialysis-related distress in people receiving hemodialysis. The program includes weekly one-on-one sessions focusing on fluid control, diet, medication adherence, and coping with symptoms. Half of the …
Sponsor: Kutahya Health Sciences University • Aim: Symptom relief
Last updated Aug 15, 2026 00:00 UTC
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Simple muscle relaxation may ease depression and fatigue in dialysis patients
Symptom relief Recruiting nowThis study tests whether progressive muscle relaxation exercises can reduce depression and fatigue in people receiving hemodialysis. Sixty patients will practice these relaxation techniques, and researchers will measure changes in their mood and energy levels. The goal is to see …
Sponsor: Istanbul Aydın University • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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Tiny dialysis study hopes magnesium tweak calms blood cells
Knowledge-focused Recruiting nowThis pilot study tests whether adjusting magnesium levels in dialysis fluid can reduce harmful blood cell activation during treatment. Fifteen adults with kidney failure will try three different dialysis fluid recipes over six weeks. Researchers will measure blood cell counts and…
Sponsor: Universitair Ziekenhuis Brussel • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC