Cystic tumor of the pancreas

This study tests a procedure that uses a thin, flexible tube with a camera and ultrasound to guide a needle into pancreatic cysts. Chemotherapy drugs are injected directly into the cyst to shrink or destroy precancerous cells. The goal is to prevent these cysts from developing in…

This study tests a procedure called EUS-RFA, which uses a thin tube with a camera and a tiny heat probe to destroy pancreatic cysts and small tumors. It is for people who cannot have surgery or choose not to. The goal is to shrink or eliminate these growths, reduce the need for f…

This study tests a less invasive procedure called endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) to treat pancreatic cysts that have a high risk of turning into cancer. About 84 adults with pancreatic cysts at least 2 cm in size and showing concerning features wil…

This study tests whether a new ultrasound technique called SMI can accurately identify benign pancreatic cysts (serous cystadenomas). Currently, many patients with these harmless cysts undergo unnecessary surgery due to diagnostic uncertainty. The study will enroll 60 patients an…

This study looks at whether a test called PanCystPro can help doctors decide the best way to treat or monitor pancreatic cysts. The test checks fluid from the cyst for certain markers to tell if it is likely to turn into cancer. About 50 adults with pancreatic cysts will take par…

This study is testing an artificial intelligence model called Cyst-AI that uses endoscopic ultrasound images and patient data to help doctors tell apart different types of pancreatic cysts. The goal is to improve diagnosis and guide treatment decisions. Researchers plan to enroll…

This study tests an artificial intelligence (AI) system that analyzes contrast-enhanced CT scans to help diagnose and manage pancreatic diseases. The AI will classify patients into three groups: needing immediate treatment, close monitoring, or routine follow-up. Researchers will…

This study looks at whether it is safe to skip placing a drain in the belly after surgery to remove part of the pancreas. About 234 adults having this surgery will be randomly assigned to get a drain or not. The goal is to see if not using a drain leads to fewer serious problems …

This study aims to create a simple, minimally invasive test to find pancreatic cancer at an early stage and track how well treatment is working. Researchers will study 700 people with pancreatic cancer, pancreatitis, or pancreatic cysts. The goal is to identify biological markers…

This study is tracking 20,000 people who have a family history of pancreatic cancer or carry genes that raise their risk. Researchers hope to find better ways to detect the disease early, when it's more treatable. Participants will be followed over time to see who develops pancre…

This study is collecting tissue and fluid samples from 160 people with suspected liver, bile duct, or pancreatic cancers. Researchers want to understand these cancers better and test new imaging and sampling tools for earlier, more accurate diagnosis. The study does not test a ne…

This study is following 1,250 people at higher risk for pancreas cancer, including those with new diabetes, pancreatic cysts, or a family history. Researchers will collect blood samples and health data twice a year for several years. The goal is to find early markers in the blood…

This study compares two minimally invasive surgical techniques—laparoscopic and robot-assisted—for removing the left side of the pancreas in people with benign or pre-cancerous growths. About 256 participants will be randomly assigned to one of the two procedures. The goal is to …