Cystic fibrosis-related diabetes
MONDO:7770003A form of diabetes mellitus unique to individuals with cystic fibrosis (CF), arising primarily from progressive fibrotic destruction of the pancreas leading to insulin deficiency, with additional contributions from insulin resistance. CFRD affects approximately 20% of adolescents and 40-50% of adults with CF. It shares features with both type 1 and type 2 diabetes but is a distinct clinical entity with its own diagnostic criteria and management guidelines.
Also known as: CF-related diabetes, CFRD
47 clinical trials for this condition and its sub-types.
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Could ozempic help cystic fibrosis diabetes? tiny study hints at yes
Disease control CompletedThis pilot study tested the drug semaglutide (a GLP-1 receptor agonist, like Ozempic) in 8 overweight or obese adults with cystic fibrosis-related diabetes who were already using insulin. The goal was to see if adding semaglutide could safely help with weight loss and improve blo…
Phase: PHASE2, PHASE3 • Sponsor: University of Minnesota • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Which insulin dosing method works best for cystic fibrosis diabetes?
Disease control CompletedThis study tested two common methods of dosing mealtime insulin in people with cystic fibrosis-related diabetes: counting carbohydrates versus using a fixed dose. Researchers used continuous glucose monitors to track blood sugar levels and see which method kept glucose in a healt…
Phase: PHASE4 • Sponsor: Jagdeesh Ullal • Aim: Disease control
Last updated Jun 27, 2026 07:54 UTC
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Cold spray may take the sting out of insulin shots — a trial puts it to the test
Symptom relief CompletedThis trial tests whether a quick cold spray on the skin before a subcutaneous insulin injection can reduce pain compared to a placebo spray. Adults in the emergency department who need at least two insulin injections receive both sprays in random order, rating their pain after ea…
Phase: NA • Sponsor: Abant Izzet Baysal University • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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Specially designed insoles could help diabetic patients walk better
Symptom relief CompletedThis study tested custom-made insoles for people with diabetic foot to see if they improve balance and walking. Twenty-five participants aged 40 to 65 with early-stage diabetic foot issues were included. The insoles were designed using pressure measurements to offload high-pressu…
Phase: NA • Sponsor: Medipol University • Aim: Symptom relief
Last updated Jul 01, 2026 00:00 UTC
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Family secrets? study maps how relatives talk about genetic health risks
Knowledge-focused CompletedThis study explored how family members share health information about genetic diseases like sickle cell, diabetes, and cancer. Over 1,000 adults completed surveys or interviews about their family health history and support. The goal was to understand social and relational factors…
Sponsor: National Human Genome Research Institute (NHGRI) • Aim: Knowledge-focused
Last updated Jul 10, 2026 00:00 UTC
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Blood test tracks diabetes risk in cystic fibrosis patients
Knowledge-focused CompletedThis study looked at whether a blood test can measure beta cell death in people with cystic fibrosis, which may help predict diabetes. About 40 participants with cystic fibrosis and healthy controls gave blood samples to check for a specific DNA marker. The goal was to understand…
Sponsor: University of Nebraska • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:04 UTC
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Talking less meds: training helps doctors cut pills for seniors
Knowledge-focused CompletedThis study tested whether special communication training for pharmacists and general practitioners helps them involve older patients in decisions to stop or lower medications for heart disease and diabetes. Researchers enrolled 310 patients aged 75 and older who were taking certa…
Phase: NA • Sponsor: University Medical Center Groningen • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Will tylenol fool your glucose monitor? new study investigates
Knowledge-focused CompletedThis study tested whether taking acetaminophen (like Tylenol) interferes with a new continuous glucose monitor called Biolinq. Thirty-one adults with diabetes wore the Biolinq sensor and a standard CGM for three days. On day three, they took acetaminophen and researchers compared…
Phase: NA • Sponsor: Biolinq Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:04 UTC
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Sleep and blood sugar link explored in cystic fibrosis diabetes study
Knowledge-focused CompletedThis completed study looked at how blood sugar levels affect sleep in 30 adults with cystic fibrosis-related diabetes. Participants wore devices at home to track glucose and sleep for 10 days. The goal was to see if this kind of remote monitoring is practical and to gather early …
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Scientists map how lifestyle changes tweak your Body's sugar control
Knowledge-focused CompletedThis completed study looked at how diet and exercise change blood sugar levels in 61 adults with diabetes. Researchers used advanced tests (genomics, proteomics, etc.) to understand the body's complex response. The goal is to build a tool that helps doctors personalize diabetes c…
Phase: NA • Sponsor: Shanghai 6th People's Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC
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Cystic fibrosis diabetes mystery: why does it sometimes go away?
Knowledge-focused CompletedThis study followed 230 people with cystic fibrosis to understand why some develop diabetes and why it sometimes reverses. Researchers tracked genetics, lung health, infections, diet, and physical activity over a year. The goal is to improve how diabetes is screened and treated i…
Phase: NA • Sponsor: Hospices Civils de Lyon • Aim: Knowledge-focused
Last updated Jun 26, 2026 14:08 UTC