Cryoglobulinemic vasculitis
MONDO:0007407Mixed cryoglobulinemia (MC) is a rare multisystem disease characterized by the presence of circulating cryoprecipitable immune complexes in the serum, manifested clinically by a classical triad of purpura, weakness and arthralgia.
Also known as: MC, Mixed Cryoglobulinemia, essential cryoglobulinemia, essential mixed cryoglobulinemia, mixed cryoglobulinemia, primary cryoglobulinemia, Meltzer syndrome, cryoglobulinemia, familial mixed
6 clinical trials for this condition and its sub-types.
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New hope for rare vasculitis: obinutuzumab steps in where rituximab fails
Disease control Not yet recruitingThis phase 2 trial tests obinutuzumab, a drug similar to rituximab but possibly stronger, in 30 adults with active cryoglobulinemic vasculitis who did not improve or could not tolerate rituximab. The goal is to see if obinutuzumab can bring the disease under control and allow pat…
Phase: PHASE2 • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 08:02 UTC
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Blood markers may spot Kids' lung disease earlier
Knowledge-focused Not yet recruitingThis study looks at whether two substances in the blood, IL-6 and MMP-7, can help doctors diagnose and predict the course of a rare lung disease in children. Researchers will measure these markers in 60 children with immune-mediated interstitial lung disease and compare them to h…
Sponsor: Sohag University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:26 UTC