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Corneal edema
MONDO:0006712Hazy, swollen cornea.
37 clinical trials for this condition and its sub-types.
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Could a glaucoma eye drop also heal the cornea?
Disease control CompletedThis study tests whether a combination eye drop (netarsudil/latanoprost) can improve vision and reduce corneal thickness in people with glaucoma and a condition called pseudophakic bullous keratopathy, where the cornea swells after cataract surgery. Half of the 50 participants re…
Phase: PHASE2, PHASE3 • Sponsor: University Hospital Dubrava • Aim: Disease control
Last updated Jul 03, 2026 00:00 UTC
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Eye injection could replace corneal transplants for swelling
Disease control CompletedThis clinical trial tested a new treatment called AURN001 for people with corneal edema, a condition where the cornea swells due to damaged cells. The treatment is a single injection into the eye that combines donor corneal cells with a drug to help them work. The study involved …
Phase: PHASE1, PHASE2 • Sponsor: Aurion Biotech • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Saline showdown: which eye drop clears Post-Surgery swelling faster?
Symptom relief CompletedThis study tested whether a stronger (5%) or weaker (3%) saltwater eye drop works better to reduce corneal swelling after cataract surgery. 70 adults who developed swelling after surgery received one of the two treatments. The main goal was to see which drop thinned the cornea mo…
Phase: NA • Sponsor: Muhammad Aamir Latif • Aim: Symptom relief
Last updated Jun 27, 2026 12:37 UTC
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New eye insert may ease pain after cataract surgery
Symptom relief CompletedThis study tested whether a tiny eye insert called DEXTENZA, placed after cataract surgery, works better than standard eye drops alone for reducing pain and swelling. Fifty adults having cataract surgery took part. The insert slowly releases medicine over time, aiming to improve …
Phase: PHASE4 • Sponsor: Nicole Fram M.D. • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Bubble shield: new technique may save corneal cells during cataract surgery
Symptom relief CompletedThis study tested a 'gas bubble technique' to reduce damage to the cornea's inner layer after cataract surgery in 80 patients with hard cataracts. The approach aimed to help corneal cells recover and reduce swelling. Results focused on cell loss and safety, offering a potential w…
Phase: NA • Sponsor: Sichuan Provincial People's Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 08:05 UTC
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Does donor diabetes impact corneal transplant outcomes?
Knowledge-focused CompletedThis completed study looked at whether diabetes in a cornea donor affects the success of a corneal transplant called DMEK. Over 1,000 participants received a cornea from either a donor with or without diabetes. Researchers tracked graft failure and cell loss for one year to see i…
Phase: NA • Sponsor: Case Western Reserve University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:08 UTC
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New registry aims to improve corneal transplants with AI
Knowledge-focused CompletedThis study created a nationwide registry to track long-term results of corneal surgeries and diseases. Researchers collected images and data from 19 participants to help understand what makes corneal transplants successful. The goal is to use this information to develop AI that c…
Sponsor: Nitin Vaswani • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:06 UTC
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AI eye chatbot matches doctors in taking patient history
Knowledge-focused CompletedThis study tested whether a large language model (like ChatGPT) could collect medical history and suggest eye tests as well as doctors do. 172 patients with non-emergency eye problems took part. The AI's performance was compared to standard care, with senior specialists checking …
Phase: NA • Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:10 UTC