Cleft palate
MONDO:0016064Cleft palate is a fissure type embryopathy that affects the soft and hard palate to varying degrees.
Also known as: palatoschisis, uranostaphyloschisis
33 clinical trials for this condition and its sub-types.
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Broader categories
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New speech therapy approach may help children with cleft palate speak more clearly
Disease control ENROLLING_BY_INVITATIONThis trial compares two speech therapy approaches for Cantonese-speaking children and teens aged 4 to 17 who have cleft palate with or without cleft lip. One method focuses on practicing individual sounds, while the other targets the overall sound system. The goal is to see which…
Phase: NA • Sponsor: Chinese University of Hong Kong • Aim: Disease control
Last updated Jul 11, 2026 00:00 UTC
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Nerve block may cut opioid use after cleft palate repair
Symptom relief OngoingThis study tests whether a nerve block placed in the face can reduce pain and the need for strong opioid drugs after cleft palate surgery in children. The goal is to help kids start eating and drinking sooner and go home faster. The study involves 40 children having cleft palate …
Phase: PHASE4 • Sponsor: University of Florida • Aim: Symptom relief
Last updated Jul 23, 2026 00:00 UTC
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Pain-blocking shot for kids' cleft palate surgery never tested
Symptom relief TerminatedThis study planned to test whether a nerve block in the cheek area could reduce the need for morphine after cleft palate repair in children aged 5 months to 12 years. The experimental group would have received the nerve block, while the control group would not. However, the study…
Phase: NA • Sponsor: Centre Hospitalier Universitaire, Amiens • Aim: Symptom relief
Last updated Jun 27, 2026 13:07 UTC
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New dissolvable foods could ease Post-Surgery feeding for kids
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether special high-dissolving foods can improve feeding quality of life for children aged 6 months to 18 years after craniofacial surgery. Half of the 160 participants will receive these foods after surgery, while the other half will follow standard care. Re…
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Cleft care network aims to boost outcomes by sharing data
Knowledge-focused ENROLLING_BY_INVITATIONThis study brings together medical teams that treat children with cleft lip and/or palate. They will collect information on speech, hearing, dental health, and quality of life from about 1,000 patients. The goal is to compare results across centers and find ways to improve care. …
Sponsor: Duke University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:08 UTC