Chiari malformation

This study tested a new surgical procedure for people with Chiari malformation and type II skull base depression, a condition where brain tissue extends into the spinal canal. The surgery combined decompression, joint release, and fusion to relieve pressure and stabilize the spin…

This study looked at 250 people with Chiari malformation type I and syringomyelia to compare two surgical approaches: one that opens the covering of the brain and spinal cord, and another that also removes or shrinks the tonsils at the base of the brain. The goal was to see which…

This study tested a surgery performed before birth to repair a spinal defect called myelomeningocele, a severe form of spina bifida. The goal was to see if fixing the spine in the womb could reduce brain problems and nerve damage after birth. 38 pregnant women carrying fetuses wi…

This study followed 180 adults with syringomyelia, a condition where a cyst forms in the spinal cord, for up to 5 years. Researchers tracked symptoms, muscle strength, and MRI scans to learn how the disease progresses and how surgery affects outcomes. The goal was to gather knowl…

This study looked at the genetics of Chiari I malformation, a condition where part of the brain pushes into the spinal canal. Researchers analyzed DNA and family histories from 152 participants to find genes that may cause the malformation. The goal was to better understand why i…

This completed study looked for genetic causes of Chiari type I malformation, a condition where part of the brain pushes into the spinal canal. Researchers took blood samples from 40 people with the condition and their relatives to analyze their DNA. The goal was to find specific…