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Chiari malformation

MONDO:0000115

A rare genetic brain malformation characterized by displacement of the brain stem and cerebellum through the foramen magnum. It may result in hydrocephalus.

Also known as: (Arnold) Chiari malformation, Arnold-Chiari malformation, Chiari malformation

12 clinical trials for this condition and its sub-types.

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Sub-types

Chiari malformation type I (7) Chiari malformation type II (2) Chiari malformation type 3 (0) Chiari malformation type 4 (0)

Broader categories

Disease (680) Hereditary disease (176) Human disease (14) Disease of genetic or genomic mechanism (2) Disease by etiologic mechanism (0)
Trials to join now! 2 Not yet recruiting 1 Not yet finished but already full! 3 Completed 6
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  • Spinal canal shape may hold key to Chiari-Related syringomyelia

    Knowledge-focused Not yet recruiting

    This study uses advanced MRI to examine whether a deformity in the upper spinal canal is linked to syringomyelia (fluid-filled cavities in the spinal cord) in people with Chiari malformation type I. Researchers will compare MRI scans from 50 adults with Chiari malformation, with …

    Phase: NA • Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused

    Last updated Jul 24, 2026 00:00 UTC

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