Central precocious puberty
MONDO:0019165Central precocious puberty (CPP), also referred to as gonadotropin dependent precocious puberty, is an endocrine-related developmental disease characterized by the onset of pubertal changes, with development of secondary sexual characteristics and accelerated growth and bone maturation, before the normal age of puberty (8 years in girls and 9 years in boys).
Also known as: gonadotropin-dependant precocious puberty, gonadotropin-dependent precocious puberty, precocious puberty, central
14 clinical trials for this condition and its sub-types.
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Once-a-year shot could halt early puberty in kids
Disease control OngoingThis study tests a yearly injection called Debio 4326 in 56 children with central precocious puberty, a condition where puberty starts too early (before age 8 in girls, 9 in boys). The goal is to see if it can safely suppress puberty hormones back to childhood levels for a full y…
Phase: PHASE3 • Sponsor: Debiopharm International SA • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Twice-Yearly shot could halt early puberty in kids
Disease control OngoingThis phase 3 trial tests a new formulation of leuprolide (FP-001) given as two injections six months apart in 93 children with central precocious puberty—a condition where puberty starts too early. The goal is to see if it can safely pause puberty by keeping hormone levels low. I…
Phase: PHASE3 • Sponsor: Foresee Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Jun 26, 2026 19:06 UTC
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School program aims to shield kids from everyday chemicals
Prevention OngoingThis study tests if teaching children and parents about avoiding certain chemicals (like BPA) can actually lower the levels found in kids' urine. About 700 children aged 6 to 8 in Belgium and Spain will take part in a school program over two and a half years. The goal is to see i…
Phase: NA • Sponsor: Sciensano • Aim: Prevention
Last updated Jun 27, 2026 09:05 UTC
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Brain scans reveal hidden links between body diseases and metabolism
Knowledge-focused OngoingThis study watches 200 people with lung, gut, or hormone diseases over time using special brain scans (PET). It aims to see how these diseases change brain activity and whether those changes can predict tumor return, spread, or survival. No new treatment is tested—just observatio…
Sponsor: The First Affiliated Hospital of Zhengzhou University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC