Once-a-year shot could halt early puberty in kids
NCT ID NCT06129539
First seen Jun 27, 2026 · Last updated Jul 28, 2026 · Updated 2 times
Summary
This study tests a yearly injection called Debio 4326 in 56 children with central precocious puberty, a condition where puberty starts too early (before age 8 in girls, 9 in boys). The goal is to see if it can safely suppress puberty hormones back to childhood levels for a full year. The treatment aims to control the condition, not cure it, and children may need ongoing management.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CPQuali Pesquisa Clinica
São Paulo, 01228000, Brazil
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Centro Medico Dra Laura Maffei Investigacion Clinica Aplicada
Buenos Aires, C1425AGC, Argentina
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Centro de Investigaciones Medicas Mar del Plata
Mar del Plata, B7600FYK, Argentina
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Christus Latam Hub Center of Excellence and Innovation S C
Monterrey, 64060, Mexico
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Clinica Mayo de Urgencias Medicas Cruz Blanca S.R.L
San Miguel de Tucumán, T4000, Argentina
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Clínica de Endocrinologia e Metabologia Ltda
Lago Sul, 71625175, Brazil
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ENDOMET
Antofagasta, 1271987, Chile
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Hospital Clinico San Borja Arriaran (HCSBA)
Santiago, 8360160, Chile
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Hospital Da Criança de Brasília Jose Alencar
Brasília, 70684-831, Brazil
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Hospital Universitario Walter Cantidio
Fortaleza, 60430-270, Brazil
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Instituto de Investigaciones Metabolicas (IDIM)
Buenos Aires, C1012AAR, Argentina
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Integral Pesquisa e Ensino
Votuporanga, 15501-405, Brazil
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Irmandade Santa Casa de São Paulo
São Paulo, REG1 01222-020, Brazil
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Nucleo de Pesquisa Clínica do Rio Grande do Sul-NPCRS
Porto Alegre, 90430-001, Brazil
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Prisma Health Pediatric Endocrinology
Columbia, South Carolina, 29203, United States
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Rady Children's Hospital - San Diego
San Diego, California, 92123, United States
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University of California San Francisco-Benioff Children's Hospital
San Francisco, California, 94143, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.