Monthly shot may pause early puberty in children
NCT ID NCT07710430
First seen Jul 17, 2026 · Last updated Jul 22, 2026 · Updated 2 times
Summary
This study tests whether a monthly injection of leuprorelin, a drug that blocks puberty hormones, can safely slow or stop early puberty in children diagnosed with central precocious puberty. About 43 children—girls under 9 and boys under 10—will receive the injection every 4 weeks for 24 months. The main goal is to see if the treatment keeps puberty hormones at a low enough level to pause development.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- a hormone-blocking drug called leuprorelin
- What this could lead to
- If successful, this could confirm that monthly leuprorelin injections safely and effectively pause early puberty in children, allowing more normal growth and development.
- What could go wrong
- This is a small, single-arm study with no comparison group, so results may not be definitive. Side effects from hormone suppression can include injection-site reactions and temporary growth changes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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