Hormone blocker aims to pause early puberty in children

NCT ID NCT06926933

First seen Jul 08, 2026 · Last updated Jul 09, 2026 · Updated 1 time

Summary

This trial tests a long-acting injection of leuprolide acetate in children with central precocious puberty, a condition where puberty starts too early. The goal is to suppress puberty-related hormones, slowing or stopping early development. The study includes children aged 4 to 9 (girls) or 4 to 10 (boys) who have not yet received treatment. Researchers will measure hormone levels to see if the drug works and monitor for side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
leuprolide acetate
What this could lead to
If successful, this could provide a safe and effective way to pause early puberty in children, allowing them to grow at a normal pace.
What could go wrong
This is a small, single-group study, so results may not apply to all children. The drug may cause side effects like injection site reactions or temporary hormone changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Ajou University Medical Center

    Suwon, South Korea

  • Asan Medical Center

    Seoul, South Korea

  • Chosun University Hospital

    Kwangju, South Korea

  • Gangnam Severance Hospital

    Seoul, South Korea

  • Jeonbuk National University Hospital

    Jeonju, South Korea

  • Kangdong Sacred Heart Hospital

    Seoul, South Korea

  • Korea University Ansan Hospital

    Ansan, South Korea

  • Kyung Hee University Hospital At Gangdong

    Seoul, South Korea

  • Seoul National University Bundang Hospital

    Seongnam, South Korea

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