Central precocious puberty
MONDO:0019165Central precocious puberty (CPP), also referred to as gonadotropin dependent precocious puberty, is an endocrine-related developmental disease characterized by the onset of pubertal changes, with development of secondary sexual characteristics and accelerated growth and bone maturation, before the normal age of puberty (8 years in girls and 9 years in boys).
Also known as: gonadotropin-dependant precocious puberty, gonadotropin-dependent precocious puberty, precocious puberty, central
10 clinical trials for this condition and its sub-types.
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New injection slows down early puberty in kids
Disease control CompletedThis study tested a drug called leuprorelin to control central precocious puberty, a condition where children start puberty too early. About 80 children received an injection every 12 weeks for 6 months. The goal was to suppress hormones that drive early puberty, helping children…
Phase: PHASE4 • Sponsor: Takeda • Aim: Disease control
Last updated Aug 06, 2026 00:00 UTC
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Twice-Yearly shot could halt early puberty in kids
Disease control CompletedThis phase 3 trial tests a new formulation of leuprolide (FP-001) given as two injections six months apart in 93 children with central precocious puberty—a condition where puberty starts too early. The goal is to see if it can safely pause puberty by keeping hormone levels low. I…
Phase: PHASE3 • Sponsor: Foresee Pharmaceuticals Co., Ltd. • Aim: Disease control
Last updated Jul 22, 2026 00:00 UTC
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Blood test may help solve early puberty puzzle in girls
Knowledge-focused CompletedThis study looked at 143 girls to see if two natural chemicals in the blood, spexin and phoenixin-20, can help doctors tell the difference between true central precocious puberty and a harmless condition called premature thelarche. Researchers measured these chemicals in girls wi…
Sponsor: Kayseri City Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:13 UTC
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Big data reveals treatment trends for early puberty in chinese kids
Knowledge-focused CompletedThis study looked at medical records of 1,477 children in China diagnosed with central precocious puberty (early puberty). The goal was to see how many received treatment and how well it worked. No new treatments were tested—researchers simply collected existing information to un…
Sponsor: Takeda • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:12 UTC