Blood test may help solve early puberty puzzle in girls
NCT ID NCT07359092
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 143 girls to see if two natural chemicals in the blood, spexin and phoenixin-20, can help doctors tell the difference between true central precocious puberty and a harmless condition called premature thelarche. Researchers measured these chemicals in girls with early breast development and in healthy controls. The goal is to find a simple blood test that could guide diagnosis and avoid unnecessary treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this research could lead to a simple blood test to help doctors tell the difference between central precocious puberty and harmless early breast development.
- What could go wrong
- This is a small, completed observational study, not a treatment trial. The findings need to be confirmed in larger, more diverse groups before any diagnostic test becomes available.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kayseri City Hospital
Kayseri, 38080, Turkey (Türkiye)
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