Central nervous system tuberculosis
MONDO:0005696A well-circumscribed mass composed of tuberculous granulation tissue that may occur in the cerebral hemispheres, cerebellum, brain stem, or perimeningeal spaces. Multiple lesions are quite common. Management of intracranial manifestations vary with lesion site. Intracranial tuberculomas may be associated with seizures, focal neurologic deficits, and intracranial hypertension. Spinal cord tuberculomas may be associated with localized or radicular pain, weakness, sensory loss, and incontinence. Tuberculomas may arise as opportunistic infections, but also occur in immunocompetent individuals.
Also known as: central nervous system tuberculosis
14 clinical trials for this condition and its sub-types.
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Breakthrough test could save kids from deadly TB meningitis
Diagnosis CompletedThis study aimed to create a quick, simple test to diagnose tuberculous meningitis (TBM) in children. TBM is a severe form of TB that affects the brain and is hard to detect with current methods, especially in places with limited resources. Researchers tested 51 inflammatory mark…
Sponsor: University of Stellenbosch • Aim: Diagnosis
Last updated Jun 27, 2026 08:04 UTC
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Hotspot vs clinic: which TB hunt saves more lives?
Knowledge-focused CompletedThis study compares two strategies for finding undiagnosed tuberculosis (TB) in peri-urban Uganda. One strategy sets up screening at a large health clinic, while the other sends mobile screening teams into local hotspots where TB is thought to be most common. Researchers will tra…
Phase: NA • Sponsor: Johns Hopkins University • Aim: Knowledge-focused
Last updated Aug 14, 2026 00:00 UTC