Cardiac arrest
MONDO:0000745Cessation of breathing and/or cardiac function.
Also known as: circulatory arrest
406 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsBroader categories
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Can Ice-Cold saline save trauma victims in cardiac arrest?
Disease control TerminatedThis study tested a dramatic approach: rapidly cooling trauma patients whose hearts had stopped from severe bleeding. Doctors flushed ice-cold saline into the aorta to induce deep hypothermia, then performed emergency surgery to stop the bleeding before slowly rewarming the patie…
Phase: PHASE2 • Sponsor: University of Maryland, Baltimore • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Heart drug tested to fight COVID-19 complications
Disease control TerminatedThis study tested a drug called CardiolRx in 90 hospitalized COVID-19 patients who also had heart disease or risk factors like diabetes or high blood pressure. The goal was to see if the drug could lower the chance of death, needing intensive care, or having heart problems. The t…
Phase: PHASE2, PHASE3 • Sponsor: Cardiol Therapeutics Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Blood filter during heart bypass may prevent organ damage, but trial stopped early
Disease control TerminatedThis study tested a device called Efferon LPS that filters blood during heart surgery when a heart-lung machine is used. The goal was to see if it could prevent multiple organ failure, especially kidney damage. Only 14 people took part before the study was stopped, so the results…
Phase: NA • Sponsor: Efferon JSC • Aim: Disease control
Last updated Jun 27, 2026 08:03 UTC
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Less oxygen may save more lives after cardiac arrest, study hints
Disease control TerminatedThis study looked at whether giving less oxygen (aiming for 90-94% oxygen in the blood) right after a cardiac arrest outside the hospital helps more people survive to leave the hospital. It included 428 unconscious adults who had been revived and were on a breathing tube. The tri…
Phase: NA • Sponsor: Monash University • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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Heart surgery recovery: can patients manage their own precautions?
Symptom relief TerminatedThis study looked at whether letting patients manage their own recovery precautions after heart surgery leads to a better quality of life compared to following standard sternal precautions. Ten adults who had heart surgery were followed for up to a year. Researchers checked pain,…
Phase: NA • Sponsor: University of Chicago • Aim: Symptom relief
Last updated Jun 27, 2026 07:56 UTC
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Painkiller showdown: which is safer for the heart?
Knowledge-focused TerminatedThis study looked at how two common pain relievers—celecoxib (a Coxib) and naproxen (an NSAID)—affect blood clotting in people with rheumatoid arthritis who also have heart disease or are at high risk for it. All participants took low-dose aspirin daily. The goal was to see if on…
Phase: PHASE4 • Sponsor: Platelet and Thrombosis Research, LLC • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Timing of heart scans after arrest: does it matter?
Knowledge-focused TerminatedThis study looked at 212 patients who woke up after a cardiac arrest outside the hospital. Researchers compared getting a heart angiogram right away versus waiting 12-24 hours. The goal was to see if immediate imaging reduces the risk of death, shock, or another cardiac arrest. T…
Phase: NA • Sponsor: Aarhus University Hospital Skejby • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Cooling after cardiac arrest: did a new protocol reduce muscle relaxant use?
Knowledge-focused TerminatedThis study looked at whether a new anti-shivering protocol helped reduce the need for muscle relaxants in patients cooled after cardiac arrest. Researchers reviewed records of 165 patients treated between 2017 and 2021. The study was terminated early, so results are limited.
Sponsor: Methodist Health System • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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Tiny study probes how seizure meds affect brain wiring after injury
Knowledge-focused TerminatedThis pilot study aimed to see if antiseizure drugs like phenobarbital and levetiracetam change brain connectivity patterns in people with severe acute brain injury and reduced consciousness. Only 5 participants were enrolled before the study was terminated. Researchers used resti…
Phase: PHASE4 • Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:57 UTC