Caliciviridae infectious disease

This early-stage trial tested an oral norovirus vaccine in 76 healthy breastfeeding mothers to see if it is safe and can trigger immune responses in both mom and her breastmilk. The vaccine is taken as a tablet and targets two common norovirus strains. Researchers hope that antib…

This large phase 3 trial tested a new norovirus vaccine in 8,000 healthy children aged 6 months to 13 years. The vaccine targets two common norovirus strains (GⅠ.1 and GⅡ.4) that cause severe vomiting and diarrhea. Researchers compared vaccinated kids to those who got a placebo t…

This study tested an experimental oral vaccine designed to protect against norovirus, a highly contagious virus that causes vomiting and diarrhea. Healthy adults aged 18 to 49 received either a single dose of the vaccine or a placebo. About a month later, all volunteers were inte…

This study looked at whether giving hospital-level care to acutely ill adults in their own homes in rural areas works well. 160 people with various conditions like infections, heart failure, or COPD took part. The goal was to see if this approach could lower costs and help patien…

This study looked at how well a new, quick finger-prick test (LumiraDx CRP) measures CRP levels compared to a standard lab test. CRP is a marker of infection, inflammation, or tissue injury. 79 adults with symptoms of these conditions took part. The goal was to see if the new tes…

This early study tested whether a special PET scan using a radioactive form of vitamin B9 (11C-PABA) can help doctors see infections deep inside the body. Researchers scanned 13 healthy people and patients with known or suspected infections. The goal was to see if this method can…

This study looked at 156 critically ill patients to find out what factors help achieve the right levels of beta-lactam antibiotics in the blood. Researchers collected clinical data and used therapeutic drug monitoring to see which patients reached target concentrations. The goal …