Stomach flu vaccine shows promise in massive Kids' trial

NCT ID NCT05916326

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This large phase 3 trial tested a new norovirus vaccine in 8,000 healthy children aged 6 months to 13 years. The vaccine targets two common norovirus strains (GⅠ.1 and GⅡ.4) that cause severe vomiting and diarrhea. Researchers compared vaccinated kids to those who got a placebo to see if the shot prevents moderate to severe stomach flu.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Norovirus bivalent vaccine (GⅠ.1/GⅡ.4)
What this could lead to
If successful, this vaccine could protect children against the most common causes of severe vomiting and diarrhea from norovirus.
What could go wrong
This is a completed trial, but results are not yet published. The vaccine may not work against all norovirus strains, and side effects are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Jingxing County Center for Disease Control and Prevention

    Shijiazhuang, Hebei, China

  • Laishui County Center for Disease Control and Prevention

    Baoding, Hebei, China

  • Zhao County Center for Disease Control and Prevention

    Shijiazhuang, Hebei, China

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