Blindness (disorder)
MONDO:0001941The lack of vision. It is caused by neurological or physiological factors.
Also known as: blindness
74 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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Sound and sight training may restore vision after stroke
Disease control Not yet recruitingThis study tests whether a training program that pairs sounds with visual cues can help people who have lost part of their vision due to brain damage (cortical blindness). Participants will do 12 sessions where they see and hear stimuli in their blind area, plus virtual reality t…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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New artificial vein valve could help millions with leg vein disease
Disease control Not yet recruitingThis trial tests a new device called the enVVe system, a catheter-based artificial valve placed in leg veins to treat chronic venous insufficiency. The study will enroll 220 people with severe symptoms like skin changes or leg ulcers. Participants are randomly assigned to receive…
Phase: PHASE2, PHASE3 • Sponsor: Hancock Jaffe Laboratiores, Inc • Aim: Disease control
Last updated Jun 27, 2026 12:38 UTC
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Texts and calls could save sight: pakistan study tests referral boost
Prevention Not yet recruitingThis study tests whether a structured referral tracking program helps adults in Pakistan complete follow-up eye care after community screenings. 500 participants will receive either standard referral or extra support like counseling and weekly reminders. The goal is to prevent bl…
Phase: NA • Sponsor: Health Services Academy, Islamabad, Pakistan • Aim: Prevention
Last updated Jun 27, 2026 13:03 UTC
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Sound and light training may bring back sight after stroke
Symptom relief Not yet recruitingThis study tests a training technique that uses repeated flashes of light and bursts of sound to help people who have lost part of their vision after a stroke. The goal is to see if this training can improve how much they can see and how their brain responds. The study will inclu…
Phase: NA • Sponsor: Wake Forest University Health Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:23 UTC
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New wearable gadget aims to give Low-Vision users a helping hand
Symptom relief Not yet recruitingThis study explores how visual impairment affects movement and daily activities, and tests a wearable system called VIS4ION that provides audio and touch cues to help users navigate. Researchers will enroll 150 adults with visual impairment and healthy controls to see if the devi…
Phase: NA • Sponsor: NYU Langone Health • Aim: Symptom relief
Last updated Jun 27, 2026 09:09 UTC
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Magnetic pulses to the brain may help the blind see again
Symptom relief Not yet recruitingThis clinical trial tests whether transcranial magnetic stimulation (TMS) can restore vision in adults with severe retinal degeneration. Over 100 participants will receive either real TMS or a sham (fake) treatment for five days, and their eyesight will be checked up to a year la…
Phase: NA • Sponsor: Shanghai High Myopia Study Group • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Meditation or health classes may ease burden of vision loss
Symptom relief Not yet recruitingThis study tests whether meditation or a health education program can improve quality of life and mental health for people with irreversible age-related vision loss and their caregivers. About 150 participants will be assigned to either meditation training or health classes, both…
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Symptom relief
Last updated Jun 27, 2026 09:02 UTC
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AI glasses could help blind people navigate the world
Symptom relief Not yet recruitingThis study tests whether Meta AI glasses, connected to the Be My Eyes network, can help people with permanent vision loss walk and move around more easily. The glasses describe scenes and objects in real time. Fifty participants will use the glasses and report changes in their qu…
Phase: NA • Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's • Aim: Symptom relief
Last updated Jun 27, 2026 08:09 UTC
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Varicose vein treatment may ease knee pain in seniors
Symptom relief Not yet recruitingThis study looks at whether a common procedure for varicose veins—called endovenous ablation—can also reduce knee pain in people aged 80 and older. The researchers will follow 50 participants for one year after treatment, measuring pain and knee function. The goal is to see if im…
Sponsor: Chengdu University of Traditional Chinese Medicine • Aim: Symptom relief
Last updated Jun 27, 2026 07:58 UTC
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Rafting and kayaking could bridge the gap for teens with disabilities
Knowledge-focused Not yet recruitingThis study will see if outdoor activities like rafting, canyoning, and kayaking can help teens with and without disabilities feel more included and connected. About 35 teens aged 12–16 will take part, with some doing the activities and others not. Researchers will measure changes…
Phase: NA • Sponsor: Universidad de Extremadura • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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New catheter device tested for stubborn leg vein blockages
Knowledge-focused Not yet recruitingThis observational study will track 87 people who are already scheduled to receive treatment with the Recana Thrombectomy Catheter System for blocked veins in their legs. The goal is to see how safe the device is and how well it works at clearing the blockages during the procedur…
Sponsor: Intervene, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Brain study tests if sound or touch can replace sight
Knowledge-focused Not yet recruitingThis study at Stanford University will test how the brain responds when visual information is turned into patterns of sound or touch. Two hundred blind and sighted participants will use special devices (BrainPort and AI Sight) for 5 weeks. Researchers will use brain scans and per…
Phase: NA • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Premature baby eye treatments under the microscope
Knowledge-focused Not yet recruitingThis study looks at children born prematurely who had retinopathy of prematurity (ROP), a disease that can cause blindness. Some were treated with laser, others with injections, and some had ROP but no treatment. Researchers will compare their vision and retina structure to see w…
Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC
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New study hopes to help people with blurry center vision read again
Knowledge-focused Not yet recruitingThis study looks at whether shifting text to a different part of the eye can help people with central vision loss read faster and more accurately. Researchers will test 100 participants with conditions like macular degeneration using various reading tasks. The goal is to find bet…
Phase: NA • Sponsor: University of Minnesota • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Vein fix may ease aching knees, new study hints
Knowledge-focused Not yet recruitingThis study will follow 50 adults with varicose veins and chronic knee pain who are scheduled for standard vein treatment (laser or radiofrequency ablation). Researchers will measure changes in knee pain, stiffness, and function before and after the procedure. The goal is to see i…
Sponsor: Chengdu University of Traditional Chinese Medicine • Aim: Knowledge-focused
Last updated Jun 26, 2026 15:09 UTC