New artificial vein valve could help millions with leg vein disease
NCT ID NCT07609927
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This trial tests a new device called the enVVe system, a catheter-based artificial valve placed in leg veins to treat chronic venous insufficiency. The study will enroll 220 people with severe symptoms like skin changes or leg ulcers. Participants are randomly assigned to receive the valve or standard care, and researchers will measure how well the valve reduces backward blood flow and whether it is safe over 12 months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
enVVe system (a catheter-based artificial vein valve)
What this could lead to
If it works, this could offer a new treatment option for people with severe chronic venous insufficiency, potentially reducing leg swelling, pain, and ulcers.
What could go wrong
This is an early-to-mid stage trial with only 220 participants, so results may not apply to everyone. Risks include blood clots, valve infection, or the valve moving out of place.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
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