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Blood thinners after vein laser: which works best to stop dangerous clots?

NCT ID NCT07699796

Completed Prevention Sponsor: Heart, Artery, and Vein Center of Fresno Source: ClinicalTrials.gov ↗

First seen Jul 13, 2026 · Last updated Jul 17, 2026 · Updated 3 times

Summary

This trial tests whether a short 5-day course of the blood thinners rivaroxaban (Xarelto) or apixaban (Eliquis) can prevent blood clots that sometimes form after laser treatment for varicose veins. Adults with symptomatic vein reflux undergoing laser ablation of the great saphenous vein are randomly assigned to receive one of the two blood thinners or no blood thinner. The study tracks clot formation using ultrasound to see which approach is safest and most effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
rivaroxaban (Xarelto) and apixaban (Eliquis)
What this could lead to
If one blood thinner works better, it could become the standard short course to prevent clots after this common vein procedure.
What could go wrong
This is a single-centre trial, so results may not apply everywhere. Blood thinners also carry a small risk of bleeding.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

chronic venous insufficiency thrombophilia due to thrombin defect varicose disease venous insufficiency Venous Thrombosis thrombotic disease prevention target venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

VARICOSE VEINS LEG VENOUS INSUFFICIENCY (CHRONIC)(PERIPHERAL) VENOUS THROMBOSIS VENOUS THROMBOSIS DEEP (LIMBS)

Contacts and locations

Locations

  • Heart Artery and Vein Center of Fresno

    Fresno, California, 93722, United States

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