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Could leg vein disease weaken breathing and strength?

NCT ID NCT06196541

Knowledge-focused Sponsor: Izmir Democracy University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 20, 2026 · Last updated Aug 21, 2026 · Updated 1 time

Summary

This study investigates whether people with chronic venous insufficiency—a condition where leg veins struggle to return blood to the heart—experience more swelling, pain, and weakness than healthy people. Researchers will measure breathing muscle strength, lung function, walking ability, leg strength, and quality of life in both groups. The goal is to understand how this condition affects overall health and daily functioning.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If this study finds clear differences, it could point toward better ways to monitor and treat chronic venous insufficiency, improving daily life for those affected.
What could go wrong
This is an observational study, so it cannot prove cause and effect. Results may not apply to all people with the condition, and the findings might be too small to change practice.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

60 people

The number who actually took part.

Started

Dec 2023

Finished

Jul 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Volunteer adult individuals diagnosed with chronic venous insufficiency by a Cardiovascular Specialist and healthy volunteer adult individuals without a diagnosis of chronic venous insufficiency will be included in this study.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria for individuals with chronic venous insufficiency: * Being diagnosed with chronic venous insufficiency * Being in one of the C1, C2, C3, C4, C5 stages according to the 'Clinical, Etiologic, Anatomic, Pathophysiologic' (CEAP) scale * Volunteering to participate in the study * 18 years of age or older Exclusion criteria for individuals with chronic venous insufficiency: * Presence of arterial disease, * The presence of advanced cardiorespiratory diseases, * Orthopaedic and neurological disorders affecting walking, * Presence of acute ulcers (\< 3 months) and diabetic ulcers, * Being pregnant. * History of deep vein thrombosis, * Presence of active infection Inclusion criteria for asymptomatic healthy individuals: * 18 years of age and older * Volunteering to participate in the study * Individuals who can understand and answer questionnaires and measurements Exclusion criteria for asymptomatic healthy individuals: * Individuals with any physical or mental disability * Individuals with any acute or chronic infection and/or health problems

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Conditions

The condition(s) this trial relates to.

chronic venous insufficiency Edema Pain venous insufficiency

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Chronic venous insufficiency

Contacts and locations

Locations

  • Izmir Democracy University

    Izmir, 35140, Turkey (Türkiye)

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