Background diabetic retinopathy

This study looks at whether a single injection of the drug Aflibercept given during cataract surgery works as well as three injections (one during surgery and two more over the next two months) to stop diabetic retinopathy from getting worse. The trial will include 166 diabetic p…

This study tests whether a ginkgo biloba extract (EGb761) can slow or prevent diabetic retinopathy, an eye disease caused by diabetes. About 200 adults with long-standing diabetes will take either ginkgo or standard treatment for 2 years. Researchers will measure changes in eye b…

This early study tests NPDR-01 eye drops in 10 adults with non-proliferative diabetic retinopathy, a common eye complication of diabetes. Participants will use one drop daily for 6 months to see if it reduces tiny retinal bleeds (microaneurysms) and slows disease progression. The…

This study investigates whether the speed at which blood sugar falls after starting a new diabetes medicine affects small blood vessels in the eye. Adults with type 2 diabetes who are beginning a GLP-1 receptor agonist or an SGLT2 inhibitor will undergo advanced eye scans and blo…

This study will test a new, noninvasive camera called XyCAM CRE that measures blood flow in the back of the eye. Researchers will compare its images with standard eye tests in 350 adults with retinal disorders. The goal is to see if this camera can provide extra information to he…

This study will analyze eye and brain scans from over 200,000 people to see if eye images can predict brain diseases like small vessel disease and other health problems. Researchers will build computer models to map eye features to brain structure and disease diagnoses. No treatm…