Could one injection during cataract surgery prevent diabetic eye disease worsening?
NCT ID NCT07301775
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a single injection of the drug Aflibercept given during cataract surgery works as well as three injections (one during surgery and two more over the next two months) to stop diabetic retinopathy from getting worse. The trial will include 166 diabetic patients aged 40 and older who have non-proliferative diabetic retinopathy and cataracts. Researchers will track changes in eye health over six months to see which approach better prevents disease progression.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Aflibercept (Eylea) injection
- What this could lead to
- If it works, this could show that a single injection during cataract surgery is enough to prevent diabetic retinopathy from getting worse, reducing the need for extra injections.
- What could go wrong
- This is a small, early-phase trial with only 166 participants, so results may not apply to everyone. The study is not yet recruiting, and there is a risk of side effects from the injections, such as eye inflammation or infection.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Sahiwal Medical College and Sahiwal Teaching Hospital
Sahiwal, Punjab, Pakistan, 57000, Pakistan
-
University College of Medicine and Dentistry (UCMD)
Lahore, Punjab Province, 54000, Pakistan
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