Autonomic nervous system disorder
MONDO:0001292A disease involving the autonomic nervous system.
Also known as: autonomic nervous disease, autonomic nervous system disease, autonomic nervous system disease or disorder, disease of autonomic nervous system, disease or disorder of autonomic nervous system, disorder of autonomic nervous system, disorder of peripheral autonomic nervous system, disorder of the autonomic nervous system
209 clinical trials for this condition and its sub-types, 59 tagged with Autonomic nervous system disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Autonomic nervous system disorder
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Dysautonomia 16 trials · 64 incl. sub-types
1 sub-type
- Primary dysautonomia 52 trials Sub-types →
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Autonomic nervous system neoplasm 0 trials · 60 incl. sub-types
3 sub-types
- Paraganglioma 53 trials · 57 incl. sub-types Sub-types →
- Ganglioneuroma 5 trials Sub-types →
- Sympathetic neurilemmoma 0 trials
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Sympathetic nervous system disorder 8 trials · 28 incl. sub-types
2 sub-types
- Sympathetic paraganglioma 0 trials · 16 incl. sub-types Sub-types →
- Ganglioneuroma 5 trials Sub-types →
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Pure autonomic failure 18 trials
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Autonomic dysreflexia 11 trials
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Autonomic neuropathy 7 trials · 10 incl. sub-types
2 sub-types
- Diabetic autonomic neuropathy 7 trials
- Horner syndrome 0 trials Sub-types →
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Baroreflex failure 1 trial
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Frey syndrome 0 trials
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Chronic hiccup 0 trials
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Harlequin syndrome 0 trials
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1 sub-type
- Parasympathetic paraganglioma 0 trials Sub-types →
Most studied deeper sub-types
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Can two common drugs tame the debilitating symptoms of POTS?
Disease control Not yet recruitingThis trial investigates whether guanfacine or cromolyn sodium—two drugs already approved for other conditions—can improve physical functioning and reduce symptoms like fatigue, brain fog, and gastrointestinal issues in adults with postural orthostatic tachycardia syndrome (POTS).…
Early phase 1 • Sponsor: Johns Hopkins University • Aim: Disease control
Last updated Aug 14, 2026 00:00 UTC
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Could a simple neck device ease chronic pain and dizziness?
Symptom relief Not yet recruitingThis small pilot study is testing whether a non-invasive device that stimulates the vagus nerve (nVNS) can help people with long-term muscle and joint pain who also have problems with automatic body functions like blood pressure, digestion, and heart rate. Twelve adults with chro…
Sponsor: University of Leeds • Aim: Symptom relief
Last updated Jun 27, 2026 12:31 UTC
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Beetroot juice may boost heart recovery in diabetes
Symptom relief Not yet recruitingThis study will test whether a single dose of beetroot juice can improve blood pressure and heart rate recovery after light cycling in adults with type 2 diabetes. About 20 participants aged 40-65 will receive either beetroot juice or a placebo in random order. The goal is to see…
Sponsor: Oxford Brookes University • Aim: Symptom relief
Last updated Jun 27, 2026 12:28 UTC
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Could a simple heart-rate test reveal who is truly taking their blood pressure pills?
Knowledge-focused Not yet recruitingThis observational study looks at whether heart rate variability — a measure of the nervous system's control over the heart — is linked to how well people with resistant hypertension take their medications. Researchers will use a blood test to objectively check drug levels and co…
Sponsor: Nemocnice AGEL Trinec-Podlesi a.s. • Aim: Knowledge-focused
Last updated Jul 18, 2026 00:00 UTC
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Could a nerve block or ear stimulation prevent brain damage after a hemorrhage?
Knowledge-focused Not yet recruitingThis study looks at 300 adults with a brain bleed from a ruptured aneurysm. It tests a non-invasive headband to monitor brain blood flow and two nerve treatments (a neck injection and ear stimulation) to see if they improve brain function. The goal is to find better ways to preve…
Sponsor: University of Texas Southwestern Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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Sleep trouble linked to heart risk in lung disease patients
Knowledge-focused Not yet recruitingThis study follows 60 adults with pulmonary hypertension (high blood pressure in the lungs) for 2 years. Researchers will measure breathing problems during sleep and heart rate changes to see how they relate to the disease. No new treatment is given; participants continue their u…
Sponsor: University Hospital, Rouen • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:07 UTC
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Scientists zap vagus nerve to find the perfect frequency for heart and lung health
Knowledge-focused Not yet recruitingThis study tests how stimulating the vagus nerve at different frequencies affects heart rate, blood pressure, and breathing in 36 healthy adults. Participants will receive five different stimulation frequencies (including a sham) in random order. The goal is to find which frequen…
Sponsor: SEFA HAKTAN HATIK • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:03 UTC