Arrhythmogenic right ventricular cardiomyopathy
MONDO:0016587Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heart muscle disease that consists in progressive dystrophy of primarily the right ventricular myocardium with fibro-fatty replacement and ventricular dilation, and that is clinically characterized by ventricular arrhythmias and a risk of sudden cardiac death.
Also known as: ARVD, arrhythmogenic RVD, arrhythmogenic right ventricular cardiomyopathy, arrhythmogenic right ventricular dysplasia, right ventricular dysplasia
35 clinical trials for this condition and its sub-types.
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Broader categories
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Old drug, new hope for right heart failure?
Disease control CompletedThis study tested the drug spironolactone in 15 adults with chronic right-sided heart failure. The goal was to see if it is safe and can improve heart function and reduce stress on the heart. Participants took either the drug or a placebo to compare effects.
Phase: PHASE4 • Sponsor: Ottawa Heart Institute Research Corporation • Aim: Disease control
Last updated Jun 27, 2026 12:29 UTC
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Experimental antibody IC14 tested in rare heart condition
Disease control CompletedThis early-phase trial tested IC14 (atibuclimab), an antibody that targets inflammation, in one person with arrhythmogenic cardiomyopathy (ACM), a rare heart muscle disease that can cause dangerous heart rhythms. The study measured safety, blood markers of inflammation, and heart…
Phase: PHASE1, PHASE2 • Sponsor: Implicit Bioscience • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Heart conditions in kids: study reveals impact on daily life and play
Knowledge-focused CompletedThis study looks at how inherited heart rhythm problems (like Long QT Syndrome) and heart muscle diseases (like Hypertrophic Cardiomyopathy) affect the quality of life and physical activity of children aged 6 to 18. Researchers will compare 107 children with these conditions to 1…
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Heart cell DNA may unlock genetic clues for rare heart disease
Knowledge-focused CompletedThis study looked at whether DNA can be taken from heart muscle cells to help diagnose arrhythmogenic right ventricular cardiomyopathy (ARVC), a rare heart condition. Researchers collected cells from 34 people during a routine heart procedure. The goal was to see if the DNA from …
Phase: NA • Sponsor: University Hospital, Toulouse • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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Heart condition costs under the microscope in massive hospital study
Knowledge-focused CompletedThis study collected information from over 15,000 people hospitalized with cardiomyopathy, a heart muscle disease. Researchers looked at how much these hospital stays cost and what the money was spent on. The goal was to understand the real-world financial impact and help manage …
Sponsor: China National Center for Cardiovascular Diseases • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:35 UTC
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Pilot study probes safe exercise limits for rare heart condition
Knowledge-focused CompletedThis completed pilot study looked at how moderate exercise affects heart function and dangerous heart rhythms in 20 adults with arrhythmogenic cardiomyopathy (ACM). Participants did different types of exercise while doctors measured heart pressures and electrical activity. The go…
Phase: NA • Sponsor: Technical University of Munich • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:02 UTC