Experimental drug IC14 targets heart inflammation in rare disease

NCT ID NCT06275893

First seen Nov 01, 2025 · Last updated May 07, 2026 · Updated 28 times

Summary

This early-phase trial tested a drug called IC14 in one person with arrhythmogenic cardiomyopathy, a rare heart condition that can cause dangerous heart rhythms. The goal was to see if the drug is safe and reduces inflammation, using blood tests and heart monitoring. The study did not include a placebo group and focused on measuring changes from the participant's own starting point.

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Contacts and locations

Locations

  • Cleveland Clinic

    Cleveland, Ohio, 44195, United States

  • Washington University School of Medicine

    St Louis, Missouri, 63110, United States

Conditions

Explore the condition pages connected to this study.